| Literature DB >> 30332952 |
Yanling Zhao1, Haotian Li1, Shizhang Wei1, Xuelin Zhou1, Xiaohe Xiao2.
Abstract
Infectious diseases caused by pathogenic bacteria seriously threaten human lives. Although antibiotic therapy is effective in the treatment of bacterial infections, the overuse of antibiotics has led to an increased risk of antibiotic resistance, putting forward urgent requirements for novel antibacterial drugs. Traditional Chinese herbal medicine (TCHM) and its constituents are considered to be potential sources of new antimicrobial agents. Currently, a series of chemical compounds purified from TCHM have been reported to fight against infections by drug-resistant bacteria. In this review, we summarized the recent findings on TCHM-derived compounds treating drug-resistant bacterial infections. Further studies are still needed for the discovery of potential antibacterial components from TCHM. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: TCHM-derived compounds; Traditional Chinese Herbal Medicine (TCHM); antibacterialzzm321990effect; drug-resistant bacteria; shigellosis; tuberculosis.
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Year: 2019 PMID: 30332952 DOI: 10.2174/1389557518666181017143141
Source DB: PubMed Journal: Mini Rev Med Chem ISSN: 1389-5575 Impact factor: 3.862