Literature DB >> 3033290

Effect of internal viral sequences on the utility of retroviral vectors.

D Armentano, S F Yu, P W Kantoff, T von Ruden, W F Anderson, E Gilboa.   

Abstract

Expression of the human ADA cDNA encoded by the Moloney murine leukemia virus spliced RNA form is enhanced by intron-contained sequences. The presence of sequences corresponding to the viral gag gene in a Moloney murine leukemia virus-based vector results in the generation of 10- to 40-fold higher titers of virus.

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Year:  1987        PMID： 3033290      PMCID： PMC254147          DOI： 10.1128/JVI.61.5.1647-1650.1987

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  18 in total

1.  A restriction enzyme cleavage map of Tn5 and location of a region encoding neomycin resistance.

Authors:  R A Jorgensen; S J Rothstein; W S Reznikoff
Journal:  Mol Gen Genet       Date:  1979

2.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

3.  Nucleotide sequence of Moloney murine leukaemia virus.

Authors:  T M Shinnick; R A Lerner; J G Sutcliffe
Journal:  Nature       Date:  1981 Oct 15-21       Impact factor: 49.962

4.  Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus.

Authors:  R Mann; R C Mulligan; D Baltimore
Journal:  Cell       Date:  1983-05       Impact factor: 41.582

5.  A new sensitive method for qualitative and quantitative assay of neomycin phosphotransferase in crude cell extracts.

Authors:  B Reiss; R Sprengel; H Will; H Schaller
Journal:  Gene       Date:  1984-10       Impact factor: 3.688

6.  Construction and applications of a highly transmissible murine retrovirus shuttle vector.

Authors:  C L Cepko; B E Roberts; R C Mulligan
Journal:  Cell       Date:  1984-07       Impact factor: 41.582

7.  Retrovirus transduction: segregation of the viral transforming function and the herpes simplex virus tk gene in infectious Friend spleen focus-forming virus thymidine kinase vectors.

Authors:  A L Joyner; A Bernstein
Journal:  Mol Cell Biol       Date:  1983-12       Impact factor: 4.272

8.  Noncoding region between the env and src genes of Rous sarcoma virus influences splicing efficiency at the src gene 3' splice site.

Authors:  C M Stoltzfus; S K Lorenzen; S L Berberich
Journal:  J Virol       Date:  1987-01       Impact factor: 5.103

9.  Role of intron-contained sequences in formation of moloney murine leukemia virus env mRNA.

Authors:  L S Hwang; J Park; E Gilboa
Journal:  Mol Cell Biol       Date:  1984-11       Impact factor: 4.272

10.  Cloning of cDNA sequences of human adenosine deaminase.

Authors:  D A Wiginton; G S Adrian; R L Friedman; D P Suttle; J J Hutton
Journal:  Proc Natl Acad Sci U S A       Date:  1983-12       Impact factor: 11.205
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  110 in total

1.  An Mpsi-containing heterologous RNA, but not env mRNA, is efficiently packaged into avian retroviral particles.

Authors:  J D Banks; B O Kealoha; M L Linial
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

2.  Design of 5' untranslated sequences in retroviral vectors developed for medical use.

Authors:  M Hildinger; K L Abel; W Ostertag; C Baum
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

Review 3.  Retroviral vectors.

Authors:  K M Kurian; C J Watson; A H Wyllie
Journal:  Mol Pathol       Date:  2000-08

4.  The 17 nucleotides downstream from the env gene stop codon are important for murine leukemia virus packaging.

Authors:  S S Yu; J M Kim; S Kim
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

5.  High-frequency intracellular transposition of a defective mammalian provirus detected by an in situ colorimetric assay.

Authors:  T Tchenio; T Heidmann
Journal:  J Virol       Date:  1992-03       Impact factor: 5.103

6.  A new retrovirus packaging cell for gene transfer constructed from amplified long terminal repeat-free chimeric proviral genes.

Authors:  Y Takahara; K Hamada; D E Housman
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

7.  Production of high-titer helper virus-free retroviral vectors by cocultivation of packaging cells with different host ranges.

Authors:  C M Lynch; A D Miller
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

8.  Promoter interactions in retrovirus vectors introduced into fibroblasts and embryonic stem cells.

Authors:  P Soriano; G Friedrich; P Lawinger
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

9.  Defective retroviruses can disperse in the human genome by intracellular transposition.

Authors:  T Tchenio; T Heidmann
Journal:  J Virol       Date:  1991-04       Impact factor: 5.103

10.  An integration-defective U5 deletion mutant of human immunodeficiency virus type 1 reverts by eliminating additional long terminal repeat sequences.

Authors:  E Vicenzi; D S Dimitrov; A Engelman; T S Migone; D F Purcell; J Leonard; G Englund; M A Martin
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103
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