Literature DB >> 30332309

PrEP Continuation, HIV and STI Testing Rates, and Delivery of Preventive Care in a Clinic-Based Cohort.

Matthew A Hevey1, Jennifer L Walsh2, Andrew E Petroll2,3.   

Abstract

HIV pre-exposure prophylaxis (PrEP) has been demonstrated to be a safe and effective method of reducing HIV incidence. Questions remain regarding PrEP's efficacy and outcomes in real-world clinical settings. We conducted a retrospective review to assess PrEP outcomes in an academic clinic setting and focused on retention in care, reasons for discontinuation, and receipt of appropriate preventive care (immunizations, HIV testing, and STI testing). One hundred thirty-four patients were seen between 2010 and 2016 over 309 visits. One hundred sixteen patients (87%) started daily PrEP and of those, 88 (76%) attended at least one 6-month follow-up visit. Over 60% of PrEP patients completed all recommended STI screening after starting PrEP. Only 40% of patients had all appropriate immunizations at baseline; 78% had all appropriate immunizations at study completion. This study demonstrated high rates of both retention and of attaining recommended preventive care in a clinical setting outside of the rigors of clinical trials.

Entities:  

Keywords:  HIV; pre-exposure prophylaxis; prevention; preventive care; real-world clinic setting

Mesh:

Substances:

Year:  2018        PMID: 30332309      PMCID: PMC6535209          DOI: 10.1521/aeap.2018.30.5.393

Source DB:  PubMed          Journal:  AIDS Educ Prev        ISSN: 0899-9546


  22 in total

1.  Interim guidance: preexposure prophylaxis for the prevention of HIV infection in men who have sex with men.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2011-01-28       Impact factor: 17.586

2.  Preexposure prophylaxis and predicted condom use among high-risk men who have sex with men.

Authors:  Sarit A Golub; William Kowalczyk; Corina L Weinberger; Jeffrey T Parsons
Journal:  J Acquir Immune Defic Syndr       Date:  2010-08       Impact factor: 3.731

3.  Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.

Authors:  Robert M Grant; Javier R Lama; Peter L Anderson; Vanessa McMahan; Albert Y Liu; Lorena Vargas; Pedro Goicochea; Martín Casapía; Juan Vicente Guanira-Carranza; Maria E Ramirez-Cardich; Orlando Montoya-Herrera; Telmo Fernández; Valdilea G Veloso; Susan P Buchbinder; Suwat Chariyalertsak; Mauro Schechter; Linda-Gail Bekker; Kenneth H Mayer; Esper Georges Kallás; K Rivet Amico; Kathleen Mulligan; Lane R Bushman; Robert J Hance; Carmela Ganoza; Patricia Defechereux; Brian Postle; Furong Wang; J Jeff McConnell; Jia-Hua Zheng; Jeanny Lee; James F Rooney; Howard S Jaffe; Ana I Martinez; David N Burns; David V Glidden
Journal:  N Engl J Med       Date:  2010-11-23       Impact factor: 91.245

4.  Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study.

Authors:  Robert M Grant; Peter L Anderson; Vanessa McMahan; Albert Liu; K Rivet Amico; Megha Mehrotra; Sybil Hosek; Carlos Mosquera; Martin Casapia; Orlando Montoya; Susan Buchbinder; Valdilea G Veloso; Kenneth Mayer; Suwat Chariyalertsak; Linda-Gail Bekker; Esper G Kallas; Mauro Schechter; Juan Guanira; Lane Bushman; David N Burns; James F Rooney; David V Glidden
Journal:  Lancet Infect Dis       Date:  2014-07-22       Impact factor: 25.071

5.  Physician awareness of sexual orientation and preventive health recommendations to men who have sex with men.

Authors:  Andrew E Petroll; Katie E Mosack
Journal:  Sex Transm Dis       Date:  2011-01       Impact factor: 2.830

6.  Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.

Authors:  Jared M Baeten; Deborah Donnell; Patrick Ndase; Nelly R Mugo; James D Campbell; Jonathan Wangisi; Jordan W Tappero; Elizabeth A Bukusi; Craig R Cohen; Elly Katabira; Allan Ronald; Elioda Tumwesigye; Edwin Were; Kenneth H Fife; James Kiarie; Carey Farquhar; Grace John-Stewart; Aloysious Kakia; Josephine Odoyo; Akasiima Mucunguzi; Edith Nakku-Joloba; Rogers Twesigye; Kenneth Ngure; Cosmas Apaka; Harrison Tamooh; Fridah Gabona; Andrew Mujugira; Dana Panteleeff; Katherine K Thomas; Lara Kidoguchi; Meighan Krows; Jennifer Revall; Susan Morrison; Harald Haugen; Mira Emmanuel-Ogier; Lisa Ondrejcek; Robert W Coombs; Lisa Frenkel; Craig Hendrix; Namandjé N Bumpus; David Bangsberg; Jessica E Haberer; Wendy S Stevens; Jairam R Lingappa; Connie Celum
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

7.  Self-perceived risk of HIV infection and attitudes about preexposure prophylaxis among sexually transmitted disease clinic attendees in South Carolina.

Authors:  Y Omar Whiteside; Tammy Harris; Christopher Scanlon; Stephen Clarkson; Wayne Duffus
Journal:  AIDS Patient Care STDS       Date:  2011-04-06       Impact factor: 5.078

Review 8.  Pharmacists as providers of HIV pre-exposure prophylaxis.

Authors:  Christine Bruno; Parya Saberi
Journal:  Int J Clin Pharm       Date:  2012-10-17

9.  Relationship between disclosure of same-sex sexual activity to providers, HIV diagnosis and sexual health services for men who have sex with men in Vancouver, Canada.

Authors:  Brian E Ng; David Moore; Warren Michelow; Robert Hogg; Réka Gustafson; Wayne Robert; Steve Kanters; Meaghan Thumath; Marissa McGuire; Mark Gilbert
Journal:  Can J Public Health       Date:  2014-04-16

10.  No evidence of sexual risk compensation in the iPrEx trial of daily oral HIV preexposure prophylaxis.

Authors:  Julia L Marcus; David V Glidden; Kenneth H Mayer; Albert Y Liu; Susan P Buchbinder; K Rivet Amico; Vanessa McMahan; Esper Georges Kallas; Orlando Montoya-Herrera; Jose Pilotto; Robert M Grant
Journal:  PLoS One       Date:  2013-12-18       Impact factor: 3.240

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  12 in total

1.  Risk Factors Associated with Loss to Follow-up Among Transgender Women Receiving HIV Pre-exposure Prophylaxis in Chiang Mai province, Thailand.

Authors:  Natthapat Thongsak; Natthaporn Manojai; Rathawit Apiputhipan; Nicha Rongram; Natnita Mattawanon; Walaithip Bunyatisai; Bandhita Plubin; Nawapon Nakharutai; Salinee Thumronglaohapun; Pimwarat Srikummoon; Kanokkan Wongsawat; Patrinee Traisathit; Nontiya Homkham
Journal:  AIDS Behav       Date:  2022-08-05

2.  PrEP user profiles, dynamics of PrEP use and follow-up: a cohort analysis at a Belgian HIV centre (2017-2020).

Authors:  Anke Rotsaert; Thijs Reyniers; Bart K M Jacobs; Thibaut Vanbaelen; Christophe Burm; Chris Kenyon; Bea Vuylsteke; Eric Florence
Journal:  J Int AIDS Soc       Date:  2022-07       Impact factor: 6.707

3.  Reasons for PrEP Discontinuation After Navigation at Sexual Health Clinics: Interactions Among Systemic Barriers, Behavioral Relevance, and Medication Concerns.

Authors:  Zoe D Unger; Sarit A Golub; Christine Borges; Zoe R Edelstein; Trevor Hedberg; Julie Myers
Journal:  J Acquir Immune Defic Syndr       Date:  2022-07-01       Impact factor: 3.771

Review 4.  Initiation, discontinuation, and restarting HIV pre-exposure prophylaxis: ongoing implementation strategies.

Authors:  Sarah E Rutstein; Dawn K Smith; Shona Dalal; Rachel C Baggaley; Myron S Cohen
Journal:  Lancet HIV       Date:  2020-08-27       Impact factor: 12.767

5.  Changes in Sexual Behavior, PrEP Adherence, and Access to Sexual Health Services Because of the COVID-19 Pandemic Among a Cohort of PrEP-Using MSM in the South.

Authors:  Sanjana Pampati; Kayla Emrick; Aaron J Siegler; Jeb Jones
Journal:  J Acquir Immune Defic Syndr       Date:  2021-05-01       Impact factor: 3.771

6.  A taxonomy of pragmatic measures of HIV preexposure prophylaxis use.

Authors:  Maria Pyra; Laura Rusie; Michael Castro; Kristin Keglovitz Baker; Moira McNulty; Nick Bohm; Andrei Prokurat; John Schneider
Journal:  AIDS       Date:  2020-11-01       Impact factor: 4.632

7.  Longitudinal trends in PrEP familiarity, attitudes, use and discontinuation among a national probability sample of gay and bisexual men, 2016-2018.

Authors:  Ian W Holloway; Evan A Krueger; Ilan H Meyer; Marguerita Lightfoot; David M Frost; Phillip L Hammack
Journal:  PLoS One       Date:  2020-12-31       Impact factor: 3.240

8.  Scales to Assess Knowledge, Motivation, and Self-Efficacy for HIV PrEP in Colombian MSM: PrEP-COL Study.

Authors:  Héctor F Mueses-Marín; Beatriz Alvarado-Llano; Julián Torres-Isasiga; Pilar Camargo-Plazas; Maria C Bolívar-Rocha; Ximena Galindo-Orrego; Jorge L Martínez-Cajas
Journal:  AIDS Res Treat       Date:  2021-09-07

9.  Global Epidemiologic Characteristics of Sexually Transmitted Infections Among Individuals Using Preexposure Prophylaxis for the Prevention of HIV Infection: A Systematic Review and Meta-analysis.

Authors:  Jason J Ong; Rachel C Baggaley; Teodora E Wi; Joseph D Tucker; Hongyun Fu; M Kumi Smith; Sabrina Rafael; Vanessa Anglade; Jane Falconer; Richard Ofori-Asenso; Fern Terris-Prestholt; Ioannis Hodges-Mameletzis; Philippe Mayaud
Journal:  JAMA Netw Open       Date:  2019-12-02

10.  PrEP discontinuation among Latino/a and Black MSM and transgender women: A need for PrEP support services.

Authors:  Omar Nieto; Ronald A Brooks; Amanda Landrian; Alejandra Cabral; Anne E Fehrenbacher
Journal:  PLoS One       Date:  2020-11-05       Impact factor: 3.240

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