Literature DB >> 3033117

Sidedness of ceramide-phosphoethanolamine synthesis on rat liver and brain microsomal membranes.

M Malgat, A Maurice, J Baraud.   

Abstract

Phosphatidylethanolamine:ceramide-ethanolamine-phosphotransferase catalyzes the synthesis of ceramide-phosphoethanolamine, a sphingomyelin analogue. Its localization was studied in rat liver and brain microsomes. After testing the integrity and the sidedness of microsomal vesicles, trypsin treatment of intact or deoxycholate-disrupted microsomes made it possible to conclude that both the transferase and the ceramide-phosphoethanolamine are located in the cisternal leaflet of the membrane bilayer. Using trinitrobenzenesulfonic acid as a probe, no trace of newly synthesized ceramide-phosphoethanolamine was detectable on the cytoplasmic side of the microsomes.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3033117

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


  7 in total

1.  Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice.

Authors:  Andreas Bickert; Christina Ginkel; Matthijs Kol; Katharina vom Dorp; Holger Jastrow; Joachim Degen; René L Jacobs; Dennis E Vance; Elke Winterhager; Xian-Cheng Jiang; Peter Dörmann; Pentti Somerharju; Joost C M Holthuis; Klaus Willecke
Journal:  J Lipid Res       Date:  2015-02-09       Impact factor: 5.922

2.  All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity.

Authors:  Tingbo Ding; Inamul Kabir; Yue Li; Caixia Lou; Amirfarbod Yazdanyar; Jiachen Xu; Jibin Dong; Hongwen Zhou; Taesik Park; Mohamed Boutjdir; Zhiqiang Li; Xian-Cheng Jiang
Journal:  J Lipid Res       Date:  2015-01-20       Impact factor: 5.922

3.  Ceramide phosphoethanolamine biosynthesis in Drosophila is mediated by a unique ethanolamine phosphotransferase in the Golgi lumen.

Authors:  Ana M Vacaru; Joep van den Dikkenberg; Philipp Ternes; Joost C M Holthuis
Journal:  J Biol Chem       Date:  2013-02-28       Impact factor: 5.157

4.  Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase.

Authors:  Philipp Ternes; Jos F H M Brouwers; Joep van den Dikkenberg; Joost C M Holthuis
Journal:  J Lipid Res       Date:  2009-05-19       Impact factor: 5.922

5.  Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage.

Authors:  Duska Separovic; Kentaro Hanada; Ma'In Yehya Awad Maitah; Biserka Nagy; Ivan Hang; Michael A Tainsky; Janice M Kraniak; Jacek Bielawski
Journal:  Biochem Biophys Res Commun       Date:  2007-04-23       Impact factor: 3.575

6.  Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage.

Authors:  Duska Separovic; Louie Semaan; Adi L Tarca; Ma'In Yehya Awad Maitah; Kentaro Hanada; Jacek Bielawski; Maristella Villani; Chiara Luberto
Journal:  Exp Cell Res       Date:  2008-02-29       Impact factor: 3.905

7.  Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER.

Authors:  Ana M Vacaru; Fikadu G Tafesse; Philipp Ternes; Vangelis Kondylis; Martin Hermansson; Jos F H M Brouwers; Pentti Somerharju; Catherine Rabouille; Joost C M Holthuis
Journal:  J Cell Biol       Date:  2009-06-08       Impact factor: 10.539
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.