Literature DB >> 30329075

Phenotypic switching in newly emerged multidrug-resistant pathogen Candida auris.

Meghan L Bentz1, D Joseph Sexton1, Rory M Welsh1, Anastasia P Litvintseva1.   

Abstract

Candida auris is an emerging, multidrug-resistant yeast that can spread rapidly in healthcare settings. Phenotypic switching has been observed in other Candida species and can potentially interfere with correct identification. The aim of this study is to address misidentification of C. auris by describing alternate phenotypes after broth enrichment and subculturing on CHROMagar Candida. Each isolate displayed different frequencies of phenotypic switching, suggesting a strain to strain variability. Increased knowledge of the multiple phenotypes of C. auris increases the chance of isolating and identifying C. auris by reducing the risk of discarding false negative alternate colony morphologies.

Entities:  

Year:  2018        PMID: 30329075     DOI: 10.1093/mmy/myy100

Source DB:  PubMed          Journal:  Med Mycol        ISSN: 1369-3786            Impact factor:   4.076


  6 in total

Review 1.  Tools for Detecting a "Superbug": Updates on Candida auris Testing.

Authors:  Shawn R Lockhart; Meghan M Lyman; D Joseph Sexton
Journal:  J Clin Microbiol       Date:  2022-01-05       Impact factor: 11.677

Review 2.  Molecular Diagnostics in the Times of Surveillance for Candida auris.

Authors:  Milena Kordalewska; David S Perlin
Journal:  J Fungi (Basel)       Date:  2019-08-20

Review 3.  Identification of Drug Resistant Candida auris.

Authors:  Milena Kordalewska; David S Perlin
Journal:  Front Microbiol       Date:  2019-08-20       Impact factor: 5.640

4.  Screening for Candida auris in patients admitted to eight intensive care units in England, 2017 to 2018.

Authors:  Ashley Sharp; Berit Muller-Pebody; Andre Charlett; Bharat Patel; Rebecca Gorton; Jonathan Lambourne; Martina Cummins; Adela Alcolea-Medina; Mark Wilks; Robin Smith; Damien Mack; Susan Hopkins; Andrew Dodgson; Phillipa Burns; Nelun Perera; Felicia Lim; Gopal Rao; Priya Khanna; Elizabeth Johnson; Andrew Borman; Silke Schelenz; Rebecca Guy; Joanna Conneely; Rohini J Manuel; Colin S Brown
Journal:  Euro Surveill       Date:  2021-02

Review 5.  Candida auris: Epidemiology, biology, antifungal resistance, and virulence.

Authors:  Han Du; Jian Bing; Tianren Hu; Craig L Ennis; Clarissa J Nobile; Guanghua Huang
Journal:  PLoS Pathog       Date:  2020-10-22       Impact factor: 6.823

Review 6.  Promising Drug Candidates and New Strategies for Fighting against the Emerging Superbug Candida auris.

Authors:  Muriel Billamboz; Zeeshan Fatima; Saif Hameed; Samir Jawhara
Journal:  Microorganisms       Date:  2021-03-18
  6 in total

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