Literature DB >> 30328004

MicroRNAs in the Migration of Mesenchymal Stem Cells.

Lihong He1, Huanxiang Zhang2.   

Abstract

Mesenchymal stem cells (MSCs) represent a promising source of cell-based therapies for treatment of a wide variety of injuries and diseases. Their tropism and migration to the damaged sites, which are elicited by cytokines secreted from tissues around pathology, are the prerequisite for tissue repair and regeneration. Better understanding of the elicited-migration of MSCs and discovering conditions that elevate their migration ability, will help to increase their homing to pathologies and improve therapeutic efficacy. It is increasingly recognized that microRNAs are important regulators of cell migration. Here we summarize current understanding of the microRNA-regulated migration of MSCs.

Entities:  

Keywords:  Cell migration; Cytokines; Mesenchymal stem cells; Signaling pathway; miRNAs

Mesh：

Substances：

Year:  2019        PMID： 30328004     DOI： 10.1007/s12015-018-9852-7

Source DB:  PubMed          Journal:  Stem Cell Rev Rep        ISSN： 2629-3277            Impact factor:   5.739


  79 in total

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Review 3.  Focal adhesions: paradigm for a signaling nexus.

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Journal:  Circ Res       Date:  2006-03-17       Impact factor: 17.367

4.  Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

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Journal:  Science       Date:  2005-02-18       Impact factor: 47.728

5.  TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN.

Authors:  Roger Vogelmann; Marc-Daniel Nguyen-Tat; Klaudia Giehl; Guido Adler; Doris Wedlich; Andre Menke
Journal:  J Cell Sci       Date:  2005-10-15       Impact factor: 5.285

Review 6.  Phosphoinositide 3-kinase: a key biochemical signal for cell migration in response to chemokines.

Authors:  Y Sotsios; S G Ward
Journal:  Immunol Rev       Date:  2000-10       Impact factor: 12.988

7.  Wnt signaling regulates the invasion capacity of human mesenchymal stem cells.

Authors:  Peter Neth; Marisa Ciccarella; Virginia Egea; Juergen Hoelters; Marianne Jochum; Christian Ries
Journal:  Stem Cells       Date:  2006-05-11       Impact factor: 6.277

8.  Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure.

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Review 9.  Molecular complexity and dynamics of cell-matrix adhesions.

Authors:  E Zamir; B Geiger
Journal:  J Cell Sci       Date:  2001-10       Impact factor: 5.285

10.  Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia.

Authors:  Alfonso Mora; Anthony M Davies; Luc Bertrand; Isam Sharif; Grant R Budas; Sofija Jovanović; Véronique Mouton; C Ronald Kahn; John M Lucocq; Gillian A Gray; Aleksandar Jovanović; Dario R Alessi
Journal:  EMBO J       Date:  2003-09-15       Impact factor: 11.598
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  6 in total

1.  A Retrospective Analysis of Safety and Efficacy of Wharton's Jelly Stem Cell Administration in Children with Spina Bifida.

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Journal:  Stem Cell Rev Rep       Date:  2019-10       Impact factor: 5.739

2.  Endothelial Progenitor Cells Modulate Inflammation-Associated Stroke Vasculome.

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Journal:  Stem Cell Rev Rep       Date:  2019-04       Impact factor: 5.739

3.  MiR-539-5p negatively regulates migration of rMSCs induced by Bushen Huoxue decoction through targeting Wnt5a.

Authors:  Liuchao Hu; Yamei Liu; Bin Wang; Zhifang Wu; Yingxiong Chen; Lijuan Yu; Junlang Zhu; Wei Shen; Chen Chen; Dongfeng Chen; Gang Li; Liangliang Xu; Yiwen Luo
Journal:  Int J Med Sci       Date:  2019-06-10       Impact factor: 3.738

Review 4.  Exosomes and Their Role in Cancer Progression.

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Journal:  Front Oncol       Date:  2021-03-22       Impact factor: 6.244

Review 5.  Therapeutic effects of mesenchymal stem cells-derived extracellular vesicles' miRNAs on retinal regeneration: a review.

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Journal:  Stem Cell Res Ther       Date:  2021-10-07       Impact factor: 6.832

Review 6.  Stem Cell as Vehicles of Antibody in Treatment of Lymphoma: a Novel and Potential Targeted Therapy.

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Journal:  Stem Cell Rev Rep       Date:  2020-11-17       Impact factor: 5.739
  6 in total

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