Literature DB >> 3032771

Human ferritin H and L sequences lie on ten different chromosomes.

J R McGill, S L Naylor, A Y Sakaguchi, C M Moore, D Boyd, K J Barrett, T B Shows, J W Drysdale.   

Abstract

In humans, the H (heavy) and L (light) chains of the iron-storage protein ferritin, are derived from multigene families. We have examined the chromosomal distribution of these H and L sequences by Southern analysis of hybrid cell DNA and by chromosomal in situ hybridization. Our results show that human ferritin H genes and related sequences are found on at least seven different chromosomes while L genes and related sequences are on at least three different chromosomes. Further, we have mapped the chromosomal location of expressed genes for human H and L ferritin chains and have found an H sequence which may be a useful marker for idiopathic hemochromatosis.

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Year:  1987        PMID： 3032771     DOI： 10.1007/BF00283053

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  24 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

3.  The anonymous polymorphic DNA clone D1S1, previously mapped to human chromosome 1p36 by in situ hybridization, is from chromosome 3 and is duplicated on chromosome 1.

Authors:  M E Goode; P vanTuinen; D H Ledbetter; S P Daiger
Journal:  Am J Hum Genet       Date:  1986-04       Impact factor: 11.025

4.  Genes for the 'H' subunit of human ferritin are present on a number of human chromosomes.

Authors:  S J Cragg; J Drysdale; M Worwood
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

5.  Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones.

Authors:  D Boyd; C Vecoli; D M Belcher; S K Jain; J W Drysdale
Journal:  J Biol Chem       Date:  1985-09-25       Impact factor: 5.157

6.  Localization of a gene controlling the expression of the human transferrin receptor to the region q12 leads to qter of chromosome 3.

Authors:  M van de Rijn; A H Geurts van Kessel; V Kroezen; A J van Agthoven; K Verstijnen; C Terhorst; J Hilgers
Journal:  Cytogenet Cell Genet       Date:  1983

7.  Dispersion of argininosuccinate-synthetase-like human genes to multiple autosomes and the X chromosome.

Authors:  A L Beaudet; T S Su; W E O'Brien; P D'Eustachio; P E Barker; F H Ruddle
Journal:  Cell       Date:  1982-08       Impact factor: 41.582

8.  Localization of single copy DNA sequences of G-banded human chromosomes by in situ hybridization.

Authors:  M E Harper; G F Saunders
Journal:  Chromosoma       Date:  1981       Impact factor: 4.316

9.  Hereditary hemochromatosis. Phenotypic expression of the disease.

Authors:  G E Cartwright; C Q Edwards; K Kravitz; M Skolnick; D B Amos; A Johnson; L Buskjaer
Journal:  N Engl J Med       Date:  1979-07-26       Impact factor: 91.245

10.  Mapping the locus for hereditary hemochromatosis: localization between HLA-B and HLA-A.

Authors:  C Q Edwards; L M Griffen; M M Dadone; M H Skolnick; J P Kushner
Journal:  Am J Hum Genet       Date:  1986-06       Impact factor: 11.025
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  13 in total

1.  A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload.

Authors:  J Kato; K Fujikawa; M Kanda; N Fukuda; K Sasaki; T Takayama; M Kobune; K Takada; R Takimoto; H Hamada; T Ikeda; Y Niitsu
Journal:  Am J Hum Genet       Date:  2001-05-24       Impact factor: 11.025

Review 2.  Recent advance in molecular iron metabolism: translational disorders of ferritin.

Authors:  Junji Kato; Yoshiro Niitsu
Journal:  Int J Hematol       Date:  2002-10       Impact factor: 2.490

3.  Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes.

Authors:  M J Bertram; N G Bérubé; X Hang-Swanson; Q Ran; J K Leung; S Bryce; K Spurgers; R J Bick; A Baldini; Y Ning; L J Clark; E K Parkinson; J C Barrett; J R Smith; O M Pereira-Smith
Journal:  Mol Cell Biol       Date:  1999-02       Impact factor: 4.272

4.  Selective amplification via biotin- and restriction-mediated enrichment (SABRE), a novel selective amplification procedure for detection of differentially expressed mRNAs.

Authors:  D J Lavery; L Lopez-Molina; F Fleury-Olela; U Schibler
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-24       Impact factor: 11.205

5.  Ferritin H gene polymorphism in idiopathic hemochromatosis.

Authors:  V David; P Papadopoulos; J Yaouanq; M Blayau; L Abel; E Zappone; M Perichon; J Drysdale; J Y Le Gall; M Simon
Journal:  Hum Genet       Date:  1989-01       Impact factor: 4.132

6.  Human ferritin genes: chromosomal assignments and polymorphisms.

Authors:  R A Gatti; R Shaked; T K Mohandas; W Salser
Journal:  Am J Hum Genet       Date:  1987-10       Impact factor: 11.025

Review 7.  The map of chromosome 20.

Authors:  N E Simpson
Journal:  J Med Genet       Date:  1988-12       Impact factor: 6.318

8.  Duodenal iron proteins in idiopathic hemochromatosis.

Authors:  P Whittaker; B S Skikne; A M Covell; C Flowers; A Cooke; S R Lynch; J D Cook
Journal:  J Clin Invest       Date:  1989-01       Impact factor: 14.808

9.  Polymorphism in a ferritin H gene from chromosome 6p.

Authors:  E Zappone; I Dugast; P Papadopoulos; K Theriault; V David; J V LeGall; K Summers; L Powell; J Drysdale
Journal:  Hum Genet       Date:  1991-04       Impact factor: 4.132

10.  Exclusion of ferritins and iron-responsive element (IRE)-binding proteins as candidates for the hemochromatosis gene.

Authors:  H Zheng; D Bhavsar; A Volz; A Ziegler; J Drysdale
Journal:  Hum Genet       Date:  1994-08       Impact factor: 4.132
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