Cristina Valcárcel Nazco1,2,3, Borja García Lorenzo1,2,3, Tasmania Del Pino Sedeño4, Lidia García Pérez1,2,3, Noé Brito García1, Renata Linertová1,2,3, Jorge Ferrer Rodríguez1, Iñaki Imaz Iglesia2,5, Pedro Serrano Aguilar2,3,6. 1. Fundación Canaria de Investigación Sanitaria (FUNCANIS). Santa Cruz de Tenerife. España. 2. Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC). Madrid. España. 3. Centro de Investigaciones Biomédicas de Canarias (CIBICAN). Universidad de La Laguna. Santa Cruz de Tenerife. España. 4. Departamento de Psicología Clínica, Psicobiología y Metodología. Universidad de La Laguna. Santa Cruz de Tenerife. España. 5. Agencia de Evaluación de Tecnologías Sanitarias. Instituto de Salud Carlos III. Madrid. España. 6. Servicio de Evaluación de la Dirección del Servicio Canario de la Salud (SESCS). Santa Cruz de Tenerife. España.
Abstract
BACKGROUND: Given the economic burden of seasonal influenza for the healthcare system, we performed a systematic review aiming to update available evidence on the cost-effectiveness of vaccination of seasonal influenza in different age groups, including children. METHODS: A systematic review of the literature on economic evaluations of seasonal influenza vaccination programs in children and adults was carried out. The following databases were searched (January 2013 - April 2018): Medline and PREMEDLINE, EMBASE, EconLit and databases of the Centre for Reviews and Dissemination (DARE, HTA, NHS EED). RESULTS: A total of 11 economic evaluations were included. Methodological quality of included studies was acceptable. Scientific evidence shows that seasonal influenza vaccination programs in school-age children can be a cost-effective alternative from national health system perspective and can be cost-saving from societal perspective in European countries. However, available evidence does not allow us to conclude that influenza vaccination programs in healthy adults under 65 years of age were a cost-effective alternative in our context, due to the high uncertainty and the lack of studies carried out in Spanish context. CONCLUSIONS: Vaccination programs for the prevention of seasonal influenza in school-age children (3-16 years) can be a cost-effective strategy.
BACKGROUND: Given the economic burden of seasonal influenza for the healthcare system, we performed a systematic review aiming to update available evidence on the cost-effectiveness of vaccination of seasonal influenza in different age groups, including children. METHODS: A systematic review of the literature on economic evaluations of seasonal influenza vaccination programs in children and adults was carried out. The following databases were searched (January 2013 - April 2018): Medline and PREMEDLINE, EMBASE, EconLit and databases of the Centre for Reviews and Dissemination (DARE, HTA, NHS EED). RESULTS: A total of 11 economic evaluations were included. Methodological quality of included studies was acceptable. Scientific evidence shows that seasonal influenza vaccination programs in school-age children can be a cost-effective alternative from national health system perspective and can be cost-saving from societal perspective in European countries. However, available evidence does not allow us to conclude that influenza vaccination programs in healthy adults under 65 years of age were a cost-effective alternative in our context, due to the high uncertainty and the lack of studies carried out in Spanish context. CONCLUSIONS: Vaccination programs for the prevention of seasonal influenza in school-age children (3-16 years) can be a cost-effective strategy.
Authors: Piyameth Dilokthornsakul; Le My Lan; Ammarin Thakkinstian; Raymond Hutubessy; Philipp Lambach; Nathorn Chaiyakunapruk Journal: EClinicalMedicine Date: 2022-04-21