Eric Chung1, Dongwon Kang2, Hye Sun Lee3, Eun-Suk Cho4, Joo Hee Kim4, Eun Jung Park2, Seung Hyuk Baik2, Kang Young Lee2, Jeonghyun Kang5. 1. Yonsei University College of Medicine, Seoul, South Korea. 2. Department of Surgery, Yonsei University College of Medicine, Seoul, South Korea. 3. Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, South Korea. 4. Department of Radiology, Yonsei University College of Medicine, Seoul, South Korea. 5. Department of Surgery, Yonsei University College of Medicine, Seoul, South Korea. Electronic address: ravic@naver.com.
Abstract
INTRODUCTION: In measuring tumor height for rectal cancer, rigid sigmoidoscopy (RS) is a standard modality, and the accuracy of magnetic resonance imaging(MRI) in patients with/without preoperative chemoradiotherapy (CRT) has not been fully investigated. The aim of this study was to investigate the accuracy of MRI for measuring tumor height. MATERIALS AND METHODS: Among rectal cancer patients seen between July 2006 and May 2012, the initial group (RS and MRI available at initial diagnosis) and the post-CRT group (RS and MRI available after the completion of preoperative CRT) were selected. Intra-class correlation coefficient (ICC) comparison tests were performed between RS and MRI results for each group. RESULTS: Ninety-nine and 29 patients were allocated into the initial group and the post-CRT group, respectively. The tumor heights measured by RS and MRI demonstrated a positive relationship in the scatter plot (linear regression; R2 = 0.898; p < 0.001 in the initial group, R2 = 0.696; p < 0.001 in the post-CRT group). With respect to difference of absolute value (DAV) between RS and MRI, the overall mean and standard deviation of DAV were 10.9 ± 10 mm in the initial group and 8 ± 6 mm in the post-CRT group. ICC comparison analysis revealed that inter-rater agreement of RS and MRI in the initial group was significantly better than that of the post-CRT group [ICC (95% CI) 0.946 (0.919-0.963) vs. 0.823 (0.621-0.917); p = 0.004)]. CONCLUSIONS: MRI can be used as a viable option to measure tumor height in rectal cancer even in patients who have undergone preoperative CRT.
INTRODUCTION: In measuring tumor height for rectal cancer, rigid sigmoidoscopy (RS) is a standard modality, and the accuracy of magnetic resonance imaging(MRI) in patients with/without preoperative chemoradiotherapy (CRT) has not been fully investigated. The aim of this study was to investigate the accuracy of MRI for measuring tumor height. MATERIALS AND METHODS: Among rectal cancerpatients seen between July 2006 and May 2012, the initial group (RS and MRI available at initial diagnosis) and the post-CRT group (RS and MRI available after the completion of preoperative CRT) were selected. Intra-class correlation coefficient (ICC) comparison tests were performed between RS and MRI results for each group. RESULTS: Ninety-nine and 29 patients were allocated into the initial group and the post-CRT group, respectively. The tumor heights measured by RS and MRI demonstrated a positive relationship in the scatter plot (linear regression; R2 = 0.898; p < 0.001 in the initial group, R2 = 0.696; p < 0.001 in the post-CRT group). With respect to difference of absolute value (DAV) between RS and MRI, the overall mean and standard deviation of DAV were 10.9 ± 10 mm in the initial group and 8 ± 6 mm in the post-CRT group. ICC comparison analysis revealed that inter-rater agreement of RS and MRI in the initial group was significantly better than that of the post-CRT group [ICC (95% CI) 0.946 (0.919-0.963) vs. 0.823 (0.621-0.917); p = 0.004)]. CONCLUSIONS: MRI can be used as a viable option to measure tumor height in rectal cancer even in patients who have undergone preoperative CRT.
Authors: David D B Bates; James L Fuqua; Junting Zheng; Marinela Capanu; Jennifer S Golia Pernicka; Sidra Javed-Tayyab; Viktoriya Paroder; Iva Petkovska; Marc J Gollub Journal: Abdom Radiol (NY) Date: 2020-09-17