Literature DB >> 3032654

Autoradiographic localisation of NPY receptors in rabbit kidney: comparison with rat, guinea-pig and human.

K Leys, M Schachter, P Sever.   

Abstract

In vitro labelling of neuropeptide Y binding sites with 125I-NPY was performed in rabbit kidney sections. Autoradiographic and histochemical techniques localised these binding sites to the proximal convoluted tubules and the vascular smooth muscle. In comparison, 125I-NPY binding was absent from the rat, guinea pig and human kidney. Possible physiological roles for the putative NPY receptors in rabbit renal function are discussed.

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Year:  1987        PMID: 3032654     DOI: 10.1016/0014-2999(87)90171-3

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  9 in total

Review 1.  The role of neuropeptides in cardiovascular regulation.

Authors:  D Ganten; M Paul; R E Lang
Journal:  Cardiovasc Drugs Ther       Date:  1991-02       Impact factor: 3.727

2.  Localisation and characterisation of functional vasoactive intestinal peptide receptors in feline kidney.

Authors:  N M Griffiths; N L Simmons
Journal:  Pflugers Arch       Date:  1990-04       Impact factor: 3.657

Review 3.  Recent advances in receptor research.

Authors:  M Schachter
Journal:  Postgrad Med J       Date:  1989-09       Impact factor: 2.401

4.  Neuropeptide Y (NPY) metabolism by endopeptidase-2 hinders characterization of NPY receptors in rat kidney.

Authors:  J S Price; A J Kenny; N S Huskisson; M J Brown
Journal:  Br J Pharmacol       Date:  1991-10       Impact factor: 8.739

5.  Effects of neuropeptide-Y on renal function and its interaction with sympathetic stimulation in conscious dogs.

Authors:  P B Persson; H Ehmke; B Nafz; R Lang; E Hackenthal; R Nobiling; M S Dietrich; H R Kirchheim
Journal:  J Physiol       Date:  1991-12       Impact factor: 5.182

6.  Localization and characterization of neuropeptide Y binding sites in porcine and human colon.

Authors:  D A Walsh; J Wharton; D R Blake; J M Polak
Journal:  Br J Pharmacol       Date:  1993-02       Impact factor: 8.739

Review 7.  Peptides in the mammalian cardiovascular system.

Authors:  J Wharton; S Gulbenkian
Journal:  Experientia       Date:  1987-07-15

8.  Differential effect of neuropeptide-Y on membrane potential of cells in renal arterioles of the hydronephrotic mouse.

Authors:  R Nobiling; M Gabel; P B Persson; M S Dietrich; C P Bührle
Journal:  J Physiol       Date:  1991-12       Impact factor: 5.182

9.  Expression of the human neuropeptide tyrosine Y1 receptor.

Authors:  J Wharton; L Gordon; J Byrne; H Herzog; L A Selbie; K Moore; M H Sullivan; M G Elder; G Moscoso; K M Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  1993-01-15       Impact factor: 11.205

  9 in total

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