Literature DB >> 30326522

Long-Term Outcome after Successful Lower Extremity Free Flap Salvage.

Amir K Bigdeli1, Emre Gazyakan1, Volker J Schmidt1, Christoph Bauer1, Günter Germann2, Christian A Radu1, Ulrich Kneser1, Christoph Hirche1.   

Abstract

BACKGROUND: Vascular occlusion after free flap surgery has become a rare complication but still poses a major challenge. It necessitates urgent re-exploration, but the logistic challenge to provide sufficient resources for the emergency intervention remains. The aim of this study was to analyze the long-term outcome after successful lower extremity free flap salvage.
METHODS: A single-center retrospective study including long-term follow-up was approved by the local ethics committee. From January 1999 to December 2010, a total of 581 free flaps were performed for lower extremity reconstruction. Eighty-six flaps required emergency re-exploration, of which 65 could be salvaged. Fifteen salvaged flaps were excluded from the study because of secondary amputation. Of 50 patients, 29 (6 females and 23 males) were eligible for follow-up. The mean follow-up time was 54.5 ± 32.9 months. Health-related quality of life (Short Form 36 [SF-36]) and scar quality (Vancouver Scar Scale [VSS]) were analyzed.
RESULTS: The overall flap survival rate was 94.7% and the total loss rate was 5.3%. The re-exploration rate was 14.8% (86 of 581 flaps). The salvage rate was 75.6% (65 of 86 flaps). Twenty-one free flaps were totally lost (24.4%). Partial flap loss occurred in 12 cases (14.0%); 67.5% of the vascular complications occurred during the first 24 hours, 20.9% between 24 and 72 hours, and 11.6% after more than 72 hours. The mean time from the first signs of impaired flap perfusion to re-exploration was 1.3 ± 0.4 hours, and from free tissue transfer to re-exploration was 16.2 ± 1.9 hours. The overall scar appearance was good with an average VSS score of 4.0 points. The average SF-36 physical component score was 54.4 ± 5.4 and the mental component score was 63.1 ± 10.7.
CONCLUSION: Careful monitoring and the opportunity for urgent re-exploration are the key to success for free flaps salvage. Following these principles, an acceptable long-term outcome can be achieved. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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Year:  2018        PMID: 30326522     DOI: 10.1055/s-0038-1675146

Source DB:  PubMed          Journal:  J Reconstr Microsurg        ISSN: 0743-684X            Impact factor:   2.873


  6 in total

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Authors:  William C Pederson; Luke Grome
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2.  Multidisciplinary team meetings for patients with complex extremity defects: a retrospective analysis of treatment recommendations and prognostic factors for non-implementation.

Authors:  Dimitra Kotsougiani-Fischer; Sebastian Fischer; Jan Warszawski; Paul A Gruetzner; Gregor Reiter; Christoph Hirche; Ulrich Kneser
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Authors:  Jun Ho Park; Ji-Ung Park
Journal:  Sci Rep       Date:  2022-09-20       Impact factor: 4.996

Review 4.  Contemporary approach to soft-tissue reconstruction of the lower extremity after trauma.

Authors:  Matthew R Zeiderman; Lee L Q Pu
Journal:  Burns Trauma       Date:  2021-07-30

5.  A retrospective evaluation of 182 free flaps in extremity reconstruction and review of the literature.

Authors:  Sergey Arakelyan; Emrah Aydogan; Nick Spindler; Stefan Langer; Olimpiu Bota
Journal:  GMS Interdiscip Plast Reconstr Surg DGPW       Date:  2022-01-14

6.  Comparative Effectiveness Analysis of Complex Lower Extremity Reconstruction: Outcomes and Costs for Biologically Based, Local Tissue Rearrangement, and Free Flap Reconstruction.

Authors:  Geoffrey M Kozak; Jesse Y Hsu; Robyn B Broach; Sameer Shakir; Catherine Calvert; John T Stranix; Charles Messa; L Scott Levin; Joseph M Serletti; Stephen J Kovach; John P Fischer
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  6 in total

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