Literature DB >> 30325244

Natural Killer Cell-Based Cancer Immunotherapy: A Review on 10 Years Completed Clinical Trials.

Wade Chun-Wai Suen1,2,3, Wayne Yuk-Wai Lee1,4, Kam-Tong Leung5, Xiao-Hua Pan2, Gang Li1,4,6.   

Abstract

NK cell cancer immunotherapy is an emerging anti-tumour therapeutic strategy that explores NK cell stimulation. In this review, we address strategies developed to circumvent limitations to clinical application of NK cell-based therapies, and comprehensively review the design and results of clinical trials conducted in the past 10 years (2008-2018) to test their therapeutic potential. NK cell-based immunotherapy of solid cancers remains controversial, but merit further detailed investigation.

Entities:  

Keywords:  Adoptive cell therapy; Clinical trials; Immunotherapy; Leukaemia; Natural killer cells

Mesh：

Substances：

Year:  2018        PMID： 30325244     DOI： 10.1080/07357907.2018.1515315

Source DB:  PubMed          Journal:  Cancer Invest        ISSN： 0735-7907            Impact factor:   2.176


  28 in total

Review 1.  Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models.

Authors:  Ji Ye Lim; Xiang-Dong Wang
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2020-02-05       Impact factor: 4.698

Review 2.  The Role of NK Cells and Their Exosomes in Graft Versus Host Disease and Graft Versus Leukemia.

Authors:  Alireza Zafarani; Mahsa Taghavi-Farahabadi; Mohammad Hossein Razizadeh; Mohammad Reza Amirzargar; Mansoure Mansouri; Mohammad Mahmoudi
Journal:  Stem Cell Rev Rep       Date:  2022-08-22       Impact factor: 6.692

3.  Decoding the multidimensional signatures of resident and expanded natural killer cells generated from perinatal blood.

Authors:  Leisheng Zhang; Min Liu; Baoquan Song; Wenjing Miao; Rucai Zhan; Sijun Yang; Zhihai Han; Hui Cai; Xianghong Xu; Yixiao Zhao; Zhongchao Han; Tiankang Guo; Jun Yao; Qing Huang
Journal:  Am J Cancer Res       Date:  2022-05-15       Impact factor: 5.942

Review 4.  Enhancing a Natural Killer: Modification of NK Cells for Cancer Immunotherapy.

Authors:  Rasa Islam; Aleta Pupovac; Vera Evtimov; Nicholas Boyd; Runzhe Shu; Richard Boyd; Alan Trounson
Journal:  Cells       Date:  2021-04-29       Impact factor: 6.600

Review 5.  Engineering microenvironments for manufacturing therapeutic cells.

Authors:  Brian J Kwee; Kyung E Sung
Journal:  Exp Biol Med (Maywood)       Date:  2021-07-11

6.  HCMV jogs the 'memory' of NK cells in HBV.

Authors:  Upkar S Gill; Lucy Golden-Mason
Journal:  J Hepatol       Date:  2018-12-11       Impact factor: 30.083

Review 7.  Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy.

Authors:  Liangliang Xu; Weiping Lin; Longping Wen; Gang Li
Journal:  Stem Cell Res Ther       Date:  2019-07-29       Impact factor: 6.832

8.  Intraperitoneal infusion of ex vivo-cultured allogeneic NK cells in recurrent ovarian carcinoma patients (a phase I study).

Authors:  Janneke Hoogstad-van Evert; Ruud Bekkers; Nelleke Ottevanger; Nicolaas Schaap; Willemijn Hobo; Joop H Jansen; Leon Massuger; Harry Dolstra
Journal:  Medicine (Baltimore)       Date:  2019-02       Impact factor: 1.817

9.  Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization.

Authors:  Allison B Powell; Sridevi Yadavilli; Devin Saunders; Stacey Van Pelt; Elizabeth Chorvinsky; Rachel A Burga; Shuroug Albihani; Patrick J Hanley; Zhenhua Xu; Yanxin Pei; Eric S Yvon; Eugene I Hwang; Catherine M Bollard; Javad Nazarian; Conrad Russell Y Cruz
Journal:  J Transl Med       Date:  2019-09-23       Impact factor: 5.531

Review 10.  NK Cell Plasticity in Cancer.

Authors:  Sizhe Liu; Payal Dhar; Jennifer D Wu
Journal:  J Clin Med       Date:  2019-09-19       Impact factor: 4.241
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