Literature DB >> 30325219

A rare case of Paget's disease affecting the cervical spine.

J Holton1, M Jones1, Z Klezl2, M Czyz1, M Grainger1, P Rehousek1.   

Abstract

We present the case of a 75-year-old man with a rapidly progressive cervical myelopathy on a background of a 3-year history of neck pain and a severely degenerative cervical spine. The patient developed progressive myelopathy over a six-month period and suffered from worsening kyphosis. Suspicion of an underlying oncological process prompted transfer to our tertiary referral unit. Biopsy was consistent for Paget's disease, an extremely rare diagnosis of the cervical spine. Magnetic resonance imaging revealed cord compression between C4 and C6 with associated cord signal change indicative of myelopathy. A three-level corpectomy and posterior instrumented fusion was performed. There was significant blood loss (3.5l) intraoperatively, consistent with a diagnosis of Paget's disease of the bone. Cell salvage was used, as was neuromonitoring for both the anterior and posterior part of the procedure. Postoperatively, neurological function improved slightly and the patient required community neurorehabilitation to allow independent living.

Entities:  

Keywords:  Cervical myelopathy; Cervical spine; Paget’s disease; Spinal reconstruction

Mesh:

Year:  2018        PMID: 30325219      PMCID: PMC6351871          DOI: 10.1308/rcsann.2018.0187

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  23 in total

Review 1.  Osteosarcoma in Paget's disease of bone.

Authors:  Marc F Hansen; Margaret Seton; Anand Merchant
Journal:  J Bone Miner Res       Date:  2006-12       Impact factor: 6.741

Review 2.  Surgical management of Paget's disease of bone.

Authors:  Javad Parvizi; Gregg R Klein; Franklin H Sim
Journal:  J Bone Miner Res       Date:  2006-12       Impact factor: 6.741

Review 3.  Fracture healing: the diamond concept.

Authors:  Peter V Giannoudis; Thomas A Einhorn; David Marsh
Journal:  Injury       Date:  2007-09       Impact factor: 2.586

Review 4.  Paget's disease of the spine and its management.

Authors:  A G Hadjipavlou; L N Gaitanis; P G Katonis; P Lander
Journal:  Eur Spine J       Date:  2001-10       Impact factor: 3.134

5.  Cementless total hip arthroplasty in Paget's disease of bone: a retrospective review.

Authors:  Julien Wegrzyn; Vincent Pibarot; Roland Chapurlat; Jean-Paul Carret; Jacques Béjui-Hugues; Olivier Guyen
Journal:  Int Orthop       Date:  2009-08-11       Impact factor: 3.075

Review 6.  The evidence for intraoperative neurophysiological monitoring in spine surgery: does it make a difference?

Authors:  Michael G Fehlings; Darrel S Brodke; Daniel C Norvell; Joseph R Dettori
Journal:  Spine (Phila Pa 1976)       Date:  2010-04-20       Impact factor: 3.468

7.  Paget's disease of bone in The Netherlands: a population-based radiological and biochemical survey--the Rotterdam Study.

Authors:  Marelise E M W Eekhoff; Marjolein van der Klift; Herman M Kroon; Cyrus Cooper; Albert Hofman; Huibert A P Pols; Socrates E Papapoulos
Journal:  J Bone Miner Res       Date:  2004-01-26       Impact factor: 6.741

Review 8.  Paget's disease of bone.

Authors:  Richard W Whitehouse
Journal:  Semin Musculoskelet Radiol       Date:  2002-12       Impact factor: 1.777

Review 9.  Current approach on spinal cord monitoring: the point of view of the neurologist, the anesthesiologist and the spine surgeon.

Authors:  Thomas N Pajewski; Vincent Arlet; Lawrence H Phillips
Journal:  Eur Spine J       Date:  2007-07-10       Impact factor: 3.134

Review 10.  The spine in Paget's disease.

Authors:  C Dell'Atti; V N Cassar-Pullicino; R K Lalam; B J Tins; P N M Tyrrell
Journal:  Skeletal Radiol       Date:  2007-04-05       Impact factor: 2.199

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