Literature DB >> 30325213

The emerging field of senotherapeutic drugs.

Vassilios Myrianthopoulos1,2,3.   

Abstract

Keywords:  BCL-2; NF-κB; PI3K/Akt; cellular senescence; dasatinib; drug repurposing; metformin; natural products; quercetin; senescence-associated secretory phenotype; senolytics; senomorphics; target-based drug discovery

Mesh：

Substances：

Year:  2018        PMID： 30325213     DOI： 10.4155/fmc-2018-0234

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  4 in total

Review 1.  Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats.

Authors:  Marco Malavolta; Robertina Giacconi; Dario Brunetti; Mauro Provinciali; Fabrizio Maggi
Journal:  Cells       Date:  2020-04-08       Impact factor: 6.600

2.  Metabolite Profiling of Rambutan (Nephelium lappaceum L.) Seeds Using UPLC-qTOF-MS/MS and Senomorphic Effects in Aged Human Dermal Fibroblasts.

Authors:  Yae Rin Lee; Hyo Moon Cho; Eun Jin Park; Mi Zhang; Thi Phuong Doan; Ba Wool Lee; Kyung A Cho; Won Keun Oh
Journal:  Nutrients       Date:  2020-05-15       Impact factor: 5.717

3.  Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast.

Authors:  Yoyo Chih-Yun Yu; Tony Zk Hui; Tzu-Hao Kao; Hung-Fu Liao; Chih-Yi Yang; Chia-Chun Hou; Hsin-Ting Hsieh; Jen-Yun Chang; Yi-Tzang Tsai; Marina Pinskaya; Kai-Chien Yang; Yet-Ran Chen; Antonin Morillon; Mong-Hsun Tsai; Shau-Ping Lin
Journal:  Front Cell Dev Biol       Date:  2020-03-04

Review 4.  Cell Senescence: A Nonnegligible Cell State under Survival Stress in Pathology of Intervertebral Disc Degeneration.

Authors:  Yuang Zhang; Biao Yang; Jingkai Wang; Feng Cheng; Kesi Shi; Liwei Ying; Chenggui Wang; Kaishun Xia; Xianpeng Huang; Zhe Gong; Chao Yu; Fangcai Li; Chengzhen Liang; Qixin Chen
Journal:  Oxid Med Cell Longev       Date:  2020-08-31       Impact factor: 6.543
  4 in total

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