Vinod Patel1, Neerja Singh2, Anil Kumar Saksena3, Subash Singh2, S K Sonkar4, S Mandeep Jolly5. 1. Department of Pedodontics and Preventive Dentistry, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India. 2. Department of Pedodontics and Preventive Dentistry, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttrakhand, India. 3. Department of Pharmacology, King George's Medical University, Lucknow, India. 4. Department of Anaesthesiology, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttrakhand, India. 5. Department of Pedodontics and Preventive Dentistry, Uttranchal Dental and Medical Research Institute, Dehradun, Uttrakhand, India.
Abstract
OBJECTIVES: The objective of this study was to assess the safety and efficacy of intranasal and oral dexmedetomidine for procedural sedation in pediatric dental patients. MATERIALS AND METHODS: Forty-four uncooperative American Society of Anesthesiologists Grade-I children, requiring dental treatment were randomly divided into four groups who received different doses of dexmedetomidine through intranasal and oral routes. The vital signs were monitored continuously during each visit. RESULTS: In this study, significant (P < 0.05) differences were found in the onset of sedation, duration, and recovery time between intranasal and oral groups. All vital signs were within normal physiological limits with no significant adverse effects in either of the groups. CONCLUSION: Dexmedetomidine is a safe and effective agent for procedural sedation in pediatric dental patients with intranasal route having distinct advantages over oral route.
OBJECTIVES: The objective of this study was to assess the safety and efficacy of intranasal and oral dexmedetomidine for procedural sedation in pediatric dental patients. MATERIALS AND METHODS: Forty-four uncooperative American Society of Anesthesiologists Grade-I children, requiring dental treatment were randomly divided into four groups who received different doses of dexmedetomidine through intranasal and oral routes. The vital signs were monitored continuously during each visit. RESULTS: In this study, significant (P < 0.05) differences were found in the onset of sedation, duration, and recovery time between intranasal and oral groups. All vital signs were within normal physiological limits with no significant adverse effects in either of the groups. CONCLUSION: Dexmedetomidine is a safe and effective agent for procedural sedation in pediatric dental patients with intranasal route having distinct advantages over oral route.