Literature DB >> 3032434

High-dose etoposide therapy for extensive small cell lung cancer: a Cancer and Leukemia Group B Study.

S D Luikart, K J Propert, C R Modeas, M R Green, M C Perry.   

Abstract

Twenty-one previously untreated patients with extensive small cell lung cancer were treated with etoposide, 400 mg/m2/day for 3 consecutive days. Myelosuppression was severe, with a treatment-related death rate of 28%. Five partial responses were achieved. High-dose etoposide as given in this study produced unacceptable toxicity and no complete responses.

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Year:  1987        PMID: 3032434

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


  1 in total

1.  Pharmacodynamics of three daily infusions of etoposide in patients with extensive-stage small-cell lung cancer.

Authors:  A A Miller; E A Tolley; H B Niell; C F Stewart; J P Griffin
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

  1 in total

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