Literature DB >> 30323101

Disseminated tuberculosis caused by Mycobacterium bovis presenting as a tongue base mass.

Sarah Pratt1, Arthur Henderson1, Stuart Gillett1.   

Abstract

An 80-year-old woman presented with dysphagia, odynophagia and progressive weight loss. Initial investigations suggested a large base of tongue squamous cell carcinoma. At panendoscopy, biopsies were taken which revealed granulomatous inflammation with multinucleated giant cells and areas of caseous necrosis. Acid-fast bacilli were identified on Ziehl-Neelsen stain and the appearances were consistent with Mycobacterium bovis Closer inspection of the patient's medical history revealed that she had previously undergone right hemicolectomy for an ascending colon stricture. The histology had shown granulomatous inflammation consistent with intestinal tuberculosis but no systemic treatment had been instigated at the time. This case highlights the importance of taking a detailed clinical history as well as the need to be cognisant of tuberculosis masquerading as cancer in the head and neck. © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  ear, nose and throat/otolaryngology; tb and other respiratory infections

Mesh:

Year:  2018        PMID: 30323101      PMCID: PMC6194383          DOI: 10.1136/bcr-2018-225436

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  Tuberculosis in ear, nose, and throat practice: its presentation and diagnosis.

Authors:  Bhat Nalini; Subramaniam Vinayak
Journal:  Am J Otolaryngol       Date:  2006 Jan-Feb       Impact factor: 1.808

2.  Tuberculosis of the tongue in a patient with rheumatoid arthritis treated with methotrexate and adalimumab.

Authors:  Luca Rosario Assante; Enrica Barra; Marialuisa Bocchino; Giacomo Zuccarini; Gerardo Ferrara; Alessandro Sanduzzi
Journal:  Infez Med       Date:  2014-06

3.  Investigating transmission of Mycobacterium bovis in the United Kingdom in 2005 to 2008.

Authors:  Sema Mandal; Louise Bradshaw; Laura F Anderson; Tim Brown; Jason T Evans; Francis Drobniewski; Grace Smith; John G Magee; Anne Barrett; Oliver Blatchford; Ian F Laurenson; Amie-Louise Seagar; Michael Ruddy; P Lewis White; Richard Myers; Peter Hawkey; Ibrahim Abubakar
Journal:  J Clin Microbiol       Date:  2011-03-23       Impact factor: 5.948

4.  Base of tongue tuberculosis: a case report.

Authors:  Jalal Hussaini; Somasundran Mutusamy; Rahmat Omar; Raman Rajagopalan; Prepageran Narayanan
Journal:  Acta Med Iran       Date:  2012

Review 5.  [Tuberculosis of the tongue initially suspected of tongue cancer: a case report--including the search for recent 16 cases in Japan].

Authors:  Makoto Furugen; Hideta Nakamura; Yuichiro Tamaki; Shusaku Haranaga; Satomi Yara; Futoshi Higa; Masao Tateyama; Jiro Fujita
Journal:  Kekkaku       Date:  2009-08

Review 6.  The epidemiology of Mycobacterium bovis infections in animals and man: a review.

Authors:  L M O'Reilly; C J Daborn
Journal:  Tuber Lung Dis       Date:  1995-08

7.  Base of Tongue Tuberculosis: A Case Report.

Authors:  Carlos Miguel Chiesa Estomba; Ana Sofia Araujo da Costa; Teresa Rivera Schmitz; Pedro Vaamonde Lago
Journal:  Iran J Otorhinolaryngol       Date:  2015-05
  7 in total

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