Literature DB >> 3032202

[3H]-nitrendipine binding in membranes obtained from hypoxic and reoxygenated heart.

R Matucci, F Bennardini, M L Sciammarella, C Baccaro, I Stendardi, F Franconi, A Giotti.   

Abstract

We compared the binding properties of [3H]-nitrendipine in heart membranes from normal guinea-pig heart and from hypoxic or hypoxic and reoxygenated heart. The [3H]-nitrendipine binds a single class of high capacity (Bmax 667.2 +/- 105.2) with high affinity (KD 0.14 +/- 0.02) binding sites. By contrast, in membranes of hypoxic and reoxygenated heart the Bmax decreases significantly while it remains unaffected during hypoxia. Xanthinoxidase activity is increased in hypoxic-reoxygenated hearts.

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Year:  1987        PMID： 3032202     DOI： 10.1016/0006-2952(87)90414-x

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


  4 in total

1.  Interaction of palmitoyl carnitine with calcium antagonists in myocytes.

Authors:  L Patmore; G P Duncan; M Spedding
Journal:  Br J Pharmacol       Date:  1989-06       Impact factor: 8.739

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Authors:  F T van Amsterdam; M S van Amsterdam-Magnoni; M Haas; N C Punt; J Zaagsma
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990 Jan-Feb       Impact factor: 3.000

3.  Regulation of cardiac sarcolemmal Ca2+ channels and Ca2+ transporters by thyroid hormone.

Authors:  E K Seppet; F Kolar; I M Dixon; T Hata; N S Dhalla
Journal:  Mol Cell Biochem       Date:  1993-12-22       Impact factor: 3.396

Review 4.  Modification of Ischemia/Reperfusion-Induced Alterations in Subcellular Organelles by Ischemic Preconditioning.

Authors:  Paramjit S Tappia; Anureet K Shah; Bram Ramjiawan; Naranjan S Dhalla
Journal:  Int J Mol Sci       Date:  2022-03-22       Impact factor: 5.923
  4 in total

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