Literature DB >> 3032183

Isolation of a cDNA clone for rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase.

A D Colosia, M Lively, M R el-Maghrabi, S J Pilkis.   

Abstract

A cDNA clone for rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase was isolated from a lambda gt11 rat liver expression library by antibody screening. The clone was approximately 1100 bases in length and the derived amino acid sequence contained 303 residues at the carboxyl end of the subunit. This derived amino acid sequence corresponded exactly with the actual amino acid sequence of the enzyme determined by direct sequencing of the protein.

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Year:  1987        PMID： 3032183     DOI： 10.1016/0006-291x(87)90364-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

Review 1.  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis.

Authors:  Mark H Rider; Luc Bertrand; Didier Vertommen; Paul A Michels; Guy G Rousseau; Louis Hue
Journal:  Biochem J       Date:  2004-08-01       Impact factor: 3.857

2.  Sequence of human liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Authors:  A J Lange; S J Pilkis
Journal:  Nucleic Acids Res       Date:  1990-06-25       Impact factor: 16.971

3.  Expression of the bisphosphatase domain of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in Escherichia coli.

Authors:  A Tauler; A H Rosenberg; A Colosia; F W Studier; S J Pilkis
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

4.  Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells.

Authors:  G F Späth; M C Weiss
Journal:  Mol Cell Biol       Date:  1997-04       Impact factor: 4.272

5.  Identification of transient intermediates in the bisphosphatase reaction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by 31P-NMR spectroscopy.

Authors:  D A Okar; L T Kakalis; S S Narula; I M Armitage; S J Pilkis
Journal:  Biochem J       Date:  1995-05-15       Impact factor: 3.857

6.  Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells.

Authors:  Michela Carlet; Kristina Janjetovic; Johannes Rainer; Stefan Schmidt; Renate Panzer-Grümayer; Georg Mann; Martina Prelog; Bernhard Meister; Christian Ploner; Reinhard Kofler
Journal:  BMC Cancer       Date:  2010-11-23       Impact factor: 4.430

7.  Targeting the sugar metabolism of tumors with a first-in-class 6-phosphofructo-2-kinase (PFKFB4) inhibitor.

Authors:  Jason Chesney; Jennifer Clark; Lilibeth Lanceta; John O Trent; Sucheta Telang
Journal:  Oncotarget       Date:  2015-07-20
  7 in total

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