Balbir Singh1, Shu Zhang2, Chi-Keong Ching3, Dejia Huang4, Yen-Bin Liu5, Diego A Rodriguez6, Azlan Hussin7, Young-Hoon Kim8, Alexandr Robertovich Chasnoits9, Jeffrey Cerkvenik10, Katy A Muckala10, Alan Cheng10. 1. Department of Cardiology, Medanta, The Medicity Hospital, Gurgaon, Haryana, India. 2. The Cardiac Arrhythmia Center, Fuwai Cardiovascular Hospital, Beijing, China. 3. Department of Cardiology, National Heart Centre of Singapore, Singapore. 4. Department of Cardiology, West China Hospital, Chengdu, China. 5. Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan. 6. Instituto de Cardiología, Fundación Cardio infantil, Centro Internacional de Arritmias, Bogota, Colombia and Universidad de la Sabana, Chía, Colombia. 7. Department of Cardiology, Institut Jantung Negara, Kuala Lumpur, Malaysia. 8. Cardiology Division, Korea University Medical Center, Seoul, South Korea. 9. Department of Roentgen-Endovascular Surgery, Republican Scientific Practical Centre Cardiology, Minsk, Belarus. 10. Department of Cardiac Rhythm Management, Medtronic, Mounds View, Minnesota.
Abstract
BACKGROUND: Despite available evidence that implantable cardioverter defibrillators (ICDs) reduce all-cause mortality among patients at risk for sudden cardiac death, utilization of ICDs is low especially in developing countries. OBJECTIVE: To summarize reasons for ICD or cardiac resynchronization therapy defibrillator implant refusal by patients at risk for sudden cardiac arrest (Improve SCA) in developing countries. METHODS: Primary prevention (PP) and secondary prevention (SP) patients from countries where ICD use is low were enrolled. PP patients with additional risk factors (syncope, ejection fraction < 25%, nonsustained ventricular tachycardia [NSVT], or frequent premature ventricular complexes) were further categorized as "1.5 PP patients." Candidates who declined implantation were asked for reasons for refusal. Baseline factors that may have influenced the implant decision were examined using logistic regression. RESULTS: Among 3892 patients, the implant refusal rate was 46.5% among PP patients (n = 2700), and 10.3% among SP patients (n = 1192). The most common refusal reason was inability to pay for the device (53.8%), followed by not believing in the benefits of the ICD (19.4%). Among PP ICD candidates, those with no syncope, no NSVT, no premature ventricular contractions, shorter QRS duration, no atrial arrhythmias, and no left bundle branch block were more likely to refuse implant. Among SP candidates, a history of cardiovascular surgery and no sinus node dysfunction were significant predictors of ICD refusal. Additionally, countries had significant differences in patient refusal rates among PP and SP groups. CONCLUSION: Implant refusal among PP patients is high in many countries. Increased reimbursement and better awareness of the benefits of an ICD could increase their utilization.
BACKGROUND: Despite available evidence that implantable cardioverter defibrillators (ICDs) reduce all-cause mortality among patients at risk for sudden cardiac death, utilization of ICDs is low especially in developing countries. OBJECTIVE: To summarize reasons for ICD or cardiac resynchronization therapy defibrillator implant refusal by patients at risk for sudden cardiac arrest (Improve SCA) in developing countries. METHODS: Primary prevention (PP) and secondary prevention (SP) patients from countries where ICD use is low were enrolled. PP patients with additional risk factors (syncope, ejection fraction < 25%, nonsustained ventricular tachycardia [NSVT], or frequent premature ventricular complexes) were further categorized as "1.5 PP patients." Candidates who declined implantation were asked for reasons for refusal. Baseline factors that may have influenced the implant decision were examined using logistic regression. RESULTS: Among 3892 patients, the implant refusal rate was 46.5% among PP patients (n = 2700), and 10.3% among SP patients (n = 1192). The most common refusal reason was inability to pay for the device (53.8%), followed by not believing in the benefits of the ICD (19.4%). Among PP ICD candidates, those with no syncope, no NSVT, no premature ventricular contractions, shorter QRS duration, no atrial arrhythmias, and no left bundle branch block were more likely to refuse implant. Among SP candidates, a history of cardiovascular surgery and no sinus node dysfunction were significant predictors of ICD refusal. Additionally, countries had significant differences in patient refusal rates among PP and SP groups. CONCLUSION: Implant refusal among PP patients is high in many countries. Increased reimbursement and better awareness of the benefits of an ICD could increase their utilization.
Authors: Omolade O Sogade; Rieta N Aben; Harry Eyituoyo; Nkechi C Arinze; Felix O Sogade Journal: Pacing Clin Electrophysiol Date: 2021-07-18 Impact factor: 1.976