| Literature DB >> 30318137 |
Christos Tziotzios1, Timothy Brier2, John Y W Lee2, Ryo Saito2, Chao-Kai Hsu2, Kapil Bhargava2, Catherine M Stefanato3, David A Fenton2, John A McGrath2.
Abstract
Having reviewed the diverse clinical subtypes of lichenoid disease and the postulated molecular basis thereof in the first article in this 2-part continuing medical education series, we discuss herein the existing and emerging treatment strategies in the most common clinical forms of lichenoid inflammation and provide an overview of their pharmacodynamics and evidence base. The scope of this review is not to exhaustively discuss treatment modalities for all lichenoid variants discussed in the previous article of this series. Instead, the focus will be on frequently encountered subtypes of lichen planus and on linking mechanisms of disease with mechanisms of drug action. Future directions and potential avenues for translational research will also be discussed.Entities:
Keywords: emerging drugs for lichenoid inflammation; lichen planus therapeutics; lichenoid variant therapeutics
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Year: 2018 PMID: 30318137 DOI: 10.1016/j.jaad.2018.02.013
Source DB: PubMed Journal: J Am Acad Dermatol ISSN: 0190-9622 Impact factor: 11.527