| Literature DB >> 30317145 |
Peter A Bron1, Barbara Marcelli2, Joyce Mulder2, Simon van der Els3, Luiza P Morawska2, Oscar P Kuipers2, Jan Kok2, Michiel Kleerebezem3.
Abstract
The ever-expanding genomic insight in natural diversity of lactic acid bacteria (LAB) has revived the industrial interest in traditional and natural genetic mobilization methodologies. Here, we review recent advances in horizontal gene transfer processes in LAB, including natural competence, conjugation, and phage transduction. In addition, we envision the possibilities for industrial strain improvement arising from the recent discoveries of molecular exchanges between bacteria through nanotubes and extracellular vesicles, as well as the constantly expanding genome editing possibilities using the CRISPR-Cas technology.Entities:
Mesh：
Year: 2018 PMID： 30317145 DOI： 10.1016/j.copbio.2018.09.004
Source DB: PubMed Journal: Curr Opin Biotechnol ISSN： 0958-1669 Impact factor: 9.740