Chuchu Mei1, Zhe Fang1, Ruoyu Yin2, Ruotong Yang1, Kun Tang3. 1. School of Public Health, Peking University Health Science Centre, 38 Xueyuan Rd, Beijing 100191, China. 2. Institute for Medical Humanities, Peking University Health Science Centre, 38 Xueyuan Rd, Beijing 100191, China. 3. Research Center for Public Health, Tsinghua University, Haidian District, Beijing 100084, China. Electronic address: tangkun@post.harvard.edu.
Abstract
BACKGROUND & AIMS: Population-based evidence that suggests health effects of spicy consumptions on fracture was scant. The study aimed to explore the association of spicy food intake with self-reported history of fractures in the Chinese populations. METHODS: Data was drawn from the baseline survey of a large cohort study conducted in China between 2004 and 2008. A total of 512,891 adults (including 302,632 females) were included. Frequency, strength and duration of spicy food consumption were assessed using a survey questionnaire. Fracture history was self-reported based on physician's diagnoses. Multivariate logistic regression models stratified by socio-economic factors, body mass index and other lifestyle factors were performed adjusting for potential confounders. RESULTS: The prevalence of daily spicy food intake was 30.32% in males and 29.90% in females. The adjusted odds ratios for fractures were 1.04 (95% CI: 1.01-1.07) for those who ate spicy food occasionally, 1.10 (95% CI: 1.05-1.16) for those who ate one or two days a week, 1.15 (95% CI: 1.09-1.20) for three to five days a week, and 1.12 (95% CI: 1.07-1.17) for daily consumers, compared to participants who never ate spicy food. Participants who ate weak spicy food (OR: 1.10, 95% CI: 1.14-1.23), moderate spicy food (OR: 1.11, 95% CI: 1.06-1.15) and strong spicy food (OR: 1.18, 95% CI: 1.12-1.25) were more strongly associated with self-reported history of fracture. In addition, the strengths of associations were consistently stronger with the duration of spicy food exposure. In stratified analyses, the strength of such an association appeared stronger in rural areas (OR: 1.14, 95% CI: 1.09-1.20) than urban (OR: 1.09, 95% CI: 1.05-1.12). The correlation was consistently stronger in males than in females. CONCLUSIONS: Among Chinese adults, a positive cross-sectional association between the level of spicy food intake and history of fractures was found in both sexes.
BACKGROUND & AIMS: Population-based evidence that suggests health effects of spicy consumptions on fracture was scant. The study aimed to explore the association of spicy food intake with self-reported history of fractures in the Chinese populations. METHODS: Data was drawn from the baseline survey of a large cohort study conducted in China between 2004 and 2008. A total of 512,891 adults (including 302,632 females) were included. Frequency, strength and duration of spicy food consumption were assessed using a survey questionnaire. Fracture history was self-reported based on physician's diagnoses. Multivariate logistic regression models stratified by socio-economic factors, body mass index and other lifestyle factors were performed adjusting for potential confounders. RESULTS: The prevalence of daily spicy food intake was 30.32% in males and 29.90% in females. The adjusted odds ratios for fractures were 1.04 (95% CI: 1.01-1.07) for those who ate spicy food occasionally, 1.10 (95% CI: 1.05-1.16) for those who ate one or two days a week, 1.15 (95% CI: 1.09-1.20) for three to five days a week, and 1.12 (95% CI: 1.07-1.17) for daily consumers, compared to participants who never ate spicy food. Participants who ate weak spicy food (OR: 1.10, 95% CI: 1.14-1.23), moderate spicy food (OR: 1.11, 95% CI: 1.06-1.15) and strong spicy food (OR: 1.18, 95% CI: 1.12-1.25) were more strongly associated with self-reported history of fracture. In addition, the strengths of associations were consistently stronger with the duration of spicy food exposure. In stratified analyses, the strength of such an association appeared stronger in rural areas (OR: 1.14, 95% CI: 1.09-1.20) than urban (OR: 1.09, 95% CI: 1.05-1.12). The correlation was consistently stronger in males than in females. CONCLUSIONS: Among Chinese adults, a positive cross-sectional association between the level of spicy food intake and history of fractures was found in both sexes.