Literature DB >> 30315498

Physicians' and Pharmacists' Clinical Considerations for Elderly Patients with Type 2 Diabetes Mellitus: The IMPLICA2 Study.

Josep Franch-Nadal1,2, Fermín García-Gollarte3, Alfonso Pérez Del Molino4, María L Orera-Peña5, Marta Rodríguez de Miguel5, Malena Melogno-Klinkas5, Héctor D de Paz6, Susana Aceituno6, Patricia Rodríguez-Fortúnez7.   

Abstract

BACKGROUND: Management of elderly patients with type 2 diabetes mellitus (T2DM) is complex due to their age-related conditions. Several clinical guidelines provide specific recommendations for management of these patients but little is known about their implementation in clinical practice.
OBJECTIVE: To describe physician and community pharmacist perceptions and routine clinical practice in the management of elderly T2DM patients.
METHODS: Cross-sectional study.
RESULTS: A total of 993 physicians and 999 community pharmacists completed the questionnaire. More physicians than pharmacists agreed on the need to establish more flexible HbA1c targets for elderly (79.4% vs. 30.6%; p < 0.001) and frail (92.6% vs. 31.4%; p < 0.001) patients than for the general diabetic population. HbA1c targets < 7.5% for elderly patients and < 8.5% for frail patients (as recommended by the principle guidelines) were set by 38.9% and 28.7% of physicians, respectively. Furthermore, 62.8% of physicians stated they follow guideline recommendations but, based on their prescription decisions for hypothetical patients, less than 50% were aligned with them. In addition, 73.1% of physicians monitor treatment adherence, mainly by using dispensing control (59.1%). Specific nutritional approaches for elderly patients are provided by 62.9% of physicians and 56.0% of pharmacists, whilst 57.4% and 21.7%, respectively, deliver specific physical exercise programs.
CONCLUSIONS: Low adherence to guideline recommendations (i.e. setting more stringent HbA1c targets or delaying treatment intensification) may lead to suboptimal glycaemic control in elderly patients. The standardization of processes, extensive monitoring of patient treatment adherence and providing advice regarding specific personal lifestyle habits may improve the management of elderly T2DM patients.

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Year:  2019        PMID: 30315498     DOI: 10.1007/s40261-018-0713-6

Source DB:  PubMed          Journal:  Clin Drug Investig        ISSN: 1173-2563            Impact factor:   2.859


  41 in total

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Authors:  José R González-Juanatey; Eduardo Alegría-Ezquerra; Joaquín Aznar-Costa; Vicente Bertomeu-Martínez; Josep Franch-Nadal; José L Palma-Gámizf
Journal:  Rev Esp Cardiol       Date:  2006-08       Impact factor: 4.753

2.  Adherence to clinical practice guidelines and outcomes in diabetic patients.

Authors:  Se-Won Oh; Ha Jeong Lee; Ho Jun Chin; Jee-In Hwang
Journal:  Int J Qual Health Care       Date:  2011-06-25       Impact factor: 2.038

Review 3.  European Diabetes Working Party for Older People 2011 clinical guidelines for type 2 diabetes mellitus. Executive summary.

Authors:  Alan J Sinclair; Giuseppe Paolisso; Marta Castro; Isabelle Bourdel-Marchasson; Roger Gadsby; Leocadio Rodriguez Mañas
Journal:  Diabetes Metab       Date:  2011-11       Impact factor: 6.041

Review 4.  Cardiovascular risk in diabetes: a brief review.

Authors:  J B Marks; P Raskin
Journal:  J Diabetes Complications       Date:  2000 Mar-Apr       Impact factor: 2.852

5.  Association of diabetes, comorbidities, and A1C with functional disability in older adults: results from the National Health and Nutrition Examination Survey (NHANES), 1999-2006.

Authors:  Rita Rastogi Kalyani; Christopher D Saudek; Frederick L Brancati; Elizabeth Selvin
Journal:  Diabetes Care       Date:  2010-02-25       Impact factor: 19.112

6.  Adherence to guidelines and its effects on hospitalizations with complications of type 2 diabetes.

Authors:  Frank A Sloan; M Angelyn Bethel; Paul P Lee; Derek S Brown; Mark N Feinglos
Journal:  Rev Diabet Stud       Date:  2004-05-10

7.  Physician communication and patient adherence to treatment: a meta-analysis.

Authors:  Kelly B Haskard Zolnierek; M Robin Dimatteo
Journal:  Med Care       Date:  2009-08       Impact factor: 2.983

8.  Diabetes mellitus, fasting glucose, and risk of cause-specific death.

Authors:  Alexander Thompson; Emanuele Di Angelantonio; Pei Gao; Nadeem Sarwar; Sreenivasa Rao Kondapally Seshasai; Stephen Kaptoge; Peter H Whincup; Kenneth J Mukamal; Richard F Gillum; Ingar Holme; Inger Njølstad; Astrid Fletcher; Peter Nilsson; Sarah Lewington; Rory Collins; Vilmundur Gudnason; Simon G Thompson; Naveed Sattar; Elizabeth Selvin; Frank B Hu; John Danesh
Journal:  N Engl J Med       Date:  2011-03-03       Impact factor: 91.245

9.  Improving health outcomes with better patient understanding and education.

Authors:  Robert John Adams
Journal:  Risk Manag Healthc Policy       Date:  2010-10-14

10.  Delay of insulin addition to oral combination therapy despite inadequate glycemic control: delay of insulin therapy.

Authors:  Gregory A Nichols; Yuri H Koo; Sonali N Shah
Journal:  J Gen Intern Med       Date:  2007-04       Impact factor: 5.128

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