Sajjad Khalili-Moghadam1, Parvin Mirmiran2, Zahra Bahadoran1, Fereidoun Azizi3. 1. Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2. Department of Clinical Nutrition and Diet Therapy, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. mirmiran@endocrine.ac.ir. 3. Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract
BACKGROUND/ OBJECTIVES: Type 2 diabetes (T2D) is fast increasing in recent decades. Limited prospective studies are available on Mediterranean diet protective effect against T2D development. We assessed longitudinal association of the Mediterranean diet with T2D risk in Iranian men and women. SUBJECTS/ METHODS: Diet was measured using a 168-item food frequency questionnaire in 2139 adults (free of T2D), aged 20-70 years. All individuals, based on the traditional Mediterranean diet score (MDS), received scores between 0 and 8 points. Multivariate hazard ratio (HR) and 95% confidence interval (CI) were reported for the association of T2D and the MDS, with adjustment of diabetes risk score (DRS) and dietary energy intakes. RESULTS: During follow-up, a total of 143 events occurred. Individuals who had higher intakes of fish/sea foods, legumes, nuts, and monounsaturated fatty acids (MUFAs) to saturated fatty acids (SFAs) ratio had a decreased risk of T2D. After adjustment for confounders, an inverse association was found between adherence to the MDS and T2D (HR = 0.48; 95% CI 0.27-0.83). CONCLUSIONS: Our findings demonstrated an inverse association between the Mediterranean diet score and incidence of T2D.
BACKGROUND/ OBJECTIVES:Type 2 diabetes (T2D) is fast increasing in recent decades. Limited prospective studies are available on Mediterranean diet protective effect against T2D development. We assessed longitudinal association of the Mediterranean diet with T2D risk in Iranian men and women. SUBJECTS/ METHODS: Diet was measured using a 168-item food frequency questionnaire in 2139 adults (free of T2D), aged 20-70 years. All individuals, based on the traditional Mediterranean diet score (MDS), received scores between 0 and 8 points. Multivariate hazard ratio (HR) and 95% confidence interval (CI) were reported for the association of T2D and the MDS, with adjustment of diabetes risk score (DRS) and dietary energy intakes. RESULTS: During follow-up, a total of 143 events occurred. Individuals who had higher intakes of fish/sea foods, legumes, nuts, and monounsaturated fatty acids (MUFAs) to saturated fatty acids (SFAs) ratio had a decreased risk of T2D. After adjustment for confounders, an inverse association was found between adherence to the MDS and T2D (HR = 0.48; 95% CI 0.27-0.83). CONCLUSIONS: Our findings demonstrated an inverse association between the Mediterranean diet score and incidence of T2D.
Authors: Effie Viguiliouk; Andrea J Glenn; Stephanie K Nishi; Laura Chiavaroli; Maxine Seider; Tauseef Khan; Marialaura Bonaccio; Licia Iacoviello; Sonia Blanco Mejia; David J A Jenkins; Cyril W C Kendall; Hana Kahleová; Dario Rahelić; Jordi Salas-Salvadó; John L Sievenpiper Journal: Adv Nutr Date: 2019-11-01 Impact factor: 8.701
Authors: Israa M Shatwan; Eiman A Alhinai; Balqees Alawadhi; Shelini Surendran; Najlaa M Aljefree; Noha M Almoraie Journal: Nutrients Date: 2021-03-19 Impact factor: 5.717