Literature DB >> 30314616

Researchers, Patients, and Stakeholders Evaluating Comparative-Effectiveness Research: A Mixed-Methods Study of the PCORI Reviewer Experience.

Laura P Forsythe1, Lori B Frank2, Rachel Hemphill2, A Tsahai Tafari2, Victoria Szydlowski2, Michael Lauer3, Christine Goertz4, Steven Clauser2.   

Abstract

OBJECTIVES: The Patient-Centered Outcomes Research Institute (PCORI) includes patients and stakeholders alongside scientists in reviewing research applications using unique review criteria including patient-centeredness and patient and/or stakeholder engagement. To support extension of this unique collaborative model to other funders, information from the reviewers on the review process is needed to understand how scientists and nonscientists evaluate research proposals together. Thus, this study aimed to describe reviewers' perspectives of the interactions during the in-person review panel; to examine the value and challenges of including scientists, patients, and stakeholders together; and to understand the perceived importance of PCORI's review criteria.
METHODS: This study utilized anonymous, cross-sectional surveys (N = 925 respondents from 5 funding cycles: 470 scientists, 217 patients, 238 stakeholders; survey completion rates by cycle: 70-89%) and group interviews (N = 18).
RESULTS: Reviewers of all types describe PCORI Merit Review as respectful, balanced, and one of reciprocal influence among different reviewer types. Reviewers indicate strong support and value of input from all reviewer types, receptivity to input from others, and the panel chair's incorporation of all views. Patients and stakeholders provide real-world perspectives on importance to patients, research partnership plans, and study feasibility. Challenges included concerns about a lack of technical expertise of patient/stakeholder reviewers and about scientists dominating conversations. The most important criterion for assigning final review scores was technical merit-either alone or in conjunction with patient-centeredness or patient/ stakeholder engagement.
CONCLUSIONS: PCORI Merit Reviewers' self-reports indicate that the perspectives of different reviewer types are influential in panel discussions and Merit Review outcomes.
Copyright © 2018 ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Patient-Centered Outcomes Research Institute (PCORI); comparative-effectiveness research; patient/stakeholder engagement; peer review; research proposal review

Mesh:

Year:  2018        PMID: 30314616     DOI: 10.1016/j.jval.2018.03.018

Source DB:  PubMed          Journal:  Value Health        ISSN: 1098-3015            Impact factor:   5.725


  4 in total

1.  Exploring community engaged research experiences and preferences: a multi-level qualitative investigation.

Authors:  Hae-Ra Han; Ashley Xu; Kyra J W Mendez; Safiyyah Okoye; Joycelyn Cudjoe; Mona Bahouth; Melanie Reese; Lee Bone; Cheryl Dennison-Himmelfarb
Journal:  Res Involv Engagem       Date:  2021-03-30

Review 2.  Evidence gap on antihyperglycemic pharmacotherapy in frail older adults : A systematic review.

Authors:  Claudia Bollig; Gabriel Torbahn; Jürgen Bauer; Simone Brefka; Dhayana Dallmeier; Michael Denkinger; Annette Eidam; Stefan Klöppel; Andrej Zeyfang; Sebastian Voigt-Radloff
Journal:  Z Gerontol Geriatr       Date:  2020-04-17       Impact factor: 1.281

3.  Knowledge and attitudes towards clinical trials among women with ovarian cancer: results of the ACTO study.

Authors:  Paola Mosconi; Anna Roberto; Nicoletta Cerana; Nicoletta Colombo; Florence Didier; Maurizio D'Incalci; Domenica Lorusso; Fedro Alessandro Peccatori
Journal:  J Ovarian Res       Date:  2022-04-14       Impact factor: 5.506

4.  Clinical trials proposed for the VA Cooperative Studies Program: Success rates and factors impacting approval.

Authors:  David R Burnaska; Grant D Huang; Timothy J O'Leary
Journal:  Contemp Clin Trials Commun       Date:  2021-07-09
  4 in total

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