| Literature DB >> 30310418 |
Susan E Piper1, Theresa A McDonagh1.
Abstract
Advances in chemotherapeutic agents have resulted in significantly improved cancer survival rates. Cardiac toxicity, however, has emerged as a leading cause of morbidity, both during and years after treatment. One of the most common manifestations of cardiotoxicity is that of heart failure and left ventricular systolic dysfunction. In this review, current opinions and guidelines in this field are discussed, with particular focus on the most common culprits, the anthracyclines, and the monoclonal antibody, trastuzumab.Entities:
Keywords: Heart failure; anthracyclines; chemotherapy; monoclonal antibodies; trastuzumab
Year: 2015 PMID: 30310418 PMCID: PMC6159418 DOI: 10.15420/ecr.2015.10.01.19
Source DB: PubMed Journal: Eur Cardiol ISSN: 1758-3756