Literature DB >> 30308179

Stationary distribution of a 2-island 2-allele Wright-Fisher diffusion model with slow mutation and migration rates.

Conrad J Burden1, Robert C Griffiths2.   

Abstract

The stationary distribution of the diffusion limit of the 2-island, 2-allele Wright-Fisher with small but otherwise arbitrary mutation and migration rates is investigated. Following a method developed by Burden and Tang (2016, 2017) for approximating the forward Kolmogorov equation, the stationary distribution is obtained to leading order as a set of line densities on the edges of the sample space, corresponding to states for which one island is bi-allelic and the other island is non-segregating, and a set of point masses at the corners of the sample space, corresponding to states for which both islands are simultaneously non-segregating. Analytic results for the corner probabilities and line densities are verified independently using the backward generator and for the corner probabilities using the coalescent.
Copyright © 2018 Elsevier Inc. All rights reserved.

Keywords:  Diffusion process; Migration; Subdivided population

Mesh:

Year:  2018        PMID: 30308179     DOI: 10.1016/j.tpb.2018.09.004

Source DB:  PubMed          Journal:  Theor Popul Biol        ISSN: 0040-5809            Impact factor:   1.570


  2 in total

1.  The stationary distribution of a sample from the Wright-Fisher diffusion model with general small mutation rates.

Authors:  Conrad J Burden; Robert C Griffiths
Journal:  J Math Biol       Date:  2018-11-13       Impact factor: 2.259

2.  The transition distribution of a sample from a Wright-Fisher diffusion with general small mutation rates.

Authors:  Conrad J Burden; Robert C Griffiths
Journal:  J Math Biol       Date:  2019-09-17       Impact factor: 2.259

  2 in total

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