Literature DB >> 30306871

Proteolysis Targeting Chimera (PROTAC): A Paradigm-Shifting Approach in Small Molecule Drug Discovery.

Pingyuan Wang1, Jia Zhou1.   

Abstract

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Year:  2018        PMID： 30306871     DOI： 10.2174/1568026618666181010101922

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  13 in total

Review 1.  PROTACs: great opportunities for academia and industry.

Authors:  Xiuyun Sun; Hongying Gao; Yiqing Yang; Ming He; Yue Wu; Yugang Song; Yan Tong; Yu Rao
Journal:  Signal Transduct Target Ther       Date:  2019-12-24

Review 2.  The Unexpected Noncatalytic Roles of Histone Modifiers in Development and Disease.

Authors:  Yann Aubert; Shaun Egolf; Brian C Capell
Journal:  Trends Genet       Date:  2019-07-10       Impact factor: 11.639

3.  Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington's Disease Pathology.

Authors:  Natsuko Macabuag; William Esmieu; Perla Breccia; Rebecca Jarvis; Wesley Blackaby; Ovadia Lazari; Liudvikas Urbonas; Maria Eznarriaga; Rachel Williams; Annelieke Strijbosch; Rhea Van de Bospoort; Kim Matthews; Cole Clissold; Tammy Ladduwahetty; Huw Vater; Patrick Heaphy; Douglas G Stafford; Hong-Jun Wang; John E Mangette; George McAllister; Vahri Beaumont; Thomas F Vogt; Hilary A Wilkinson; Elizabeth M Doherty; Celia Dominguez
Journal:  J Med Chem       Date:  2022-09-13       Impact factor: 8.039

Review 4.  Proteolysis-targeting chimaeras (PROTACs) as pharmacological tools and therapeutic agents: advances and future challenges.

Authors:  Chao Wang; Yujing Zhang; Tingting Zhang; Lingyu Shi; Zhongmin Geng; Dongming Xing
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

Review 5.  BET proteins: Investigating BRDT as a potential target for male contraception.

Authors:  Andrea Wisniewski; Gunda I Georg
Journal:  Bioorg Med Chem Lett       Date:  2020-01-21       Impact factor: 2.823

Review 6.  Bivalent Ligands for Protein Degradation in Drug Discovery.

Authors:  Marcel Scheepstra; Koen F W Hekking; Luc van Hijfte; Rutger H A Folmer
Journal:  Comput Struct Biotechnol J       Date:  2019-01-25       Impact factor: 7.271

7.  Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer.

Authors:  María Del Mar Noblejas-López; Cristina Nieto-Jimenez; Miguel Burgos; Mónica Gómez-Juárez; Juan Carlos Montero; Azucena Esparís-Ogando; Atanasio Pandiella; Eva M Galán-Moya; Alberto Ocaña
Journal:  J Exp Clin Cancer Res       Date:  2019-08-30

Review 8.  Resources and computational strategies to advance small molecule SARS-CoV-2 discovery: lessons from the pandemic and preparing for future health crises.

Authors:  Natesh Singh; Bruno O Villoutreix
Journal:  Comput Struct Biotechnol J       Date:  2021-04-26       Impact factor: 7.271

9.  A novel strategy to block mitotic progression for targeted therapy.

Authors:  Junlong Jack Chi; Hongchun Li; Zhuan Zhou; Javier Izquierdo-Ferrer; Yifan Xue; Cindy M Wavelet; Gary E Schiltz; Bin Zhang; Massimo Cristofanilli; Xinghua Lu; Ivet Bahar; Yong Wan
Journal:  EBioMedicine       Date:  2019-10-25       Impact factor: 8.143

Review 10.  PROTACs: great opportunities for academia and industry.

Authors:  Xiuyun Sun; Hongying Gao; Yiqing Yang; Ming He; Yue Wu; Yugang Song; Yan Tong; Yu Rao
Journal:  Signal Transduct Target Ther       Date:  2019-12-24
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