Literature DB >> 3030535

Flow cytometric and karyotypic analysis of a primary small cell carcinoma of the prostate: a xenografted cell line.

S Pittman, P J Russell, M E Jelbart, J Wass, D Raghavan.   

Abstract

A human small cell undifferentiated carcinoma of the prostate, xenografted in nude mice, was analyzed both cytogenetically and by DNA flow cytometry. The DNA content of the line indicated its stability on serial passage, and was consistent with the cytogenetic findings. The banded karyotype was hypodiploid with nonrandom losses of chromosomes #6, #7, #10, and #13. Structural rearrangements involved chromosomes #1 and #2, and there were three unidentified markers. The findings were compared with those described in other types of prostatic carcinoma.

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Year:  1987        PMID: 3030535     DOI: 10.1016/0165-4608(87)90143-9

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  5 in total

1.  Detection of tumor-associated membrane proteins in prostate and bladder carcinomas by means of protein blotting.

Authors:  S A Ford; P J Russell; M Jelbart; D Raghavan
Journal:  Urol Res       Date:  1989

2.  Cell proliferation in human tumours growing in nude mice: renal cell carcinomas, larynx and hypopharynx carcinomas.

Authors:  B Maurer-Schultze; I D Bassukas; M Böswald; M Harasim
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

3.  Spontaneous phenotypic and karyotypic progression in the SV40 transfected cell line SVG during prolonged passage in vitro.

Authors:  P Davey; A M Rauth; L Mason; L Addy
Journal:  J Neurooncol       Date:  1990-02       Impact factor: 4.130

Review 4.  Small-cell neuroendocrine carcinoma of the prostate: are heterotransplants a better experimental model?

Authors:  Lluis-A Lopez-Barcons
Journal:  Asian J Androl       Date:  2009-12-21       Impact factor: 3.285

5.  Establishing prostate cancer patient derived xenografts: lessons learned from older studies.

Authors:  Pamela J Russell; Peter Russell; Christina Rudduck; Brian W C Tse; Elizabeth D Williams; Derek Raghavan
Journal:  Prostate       Date:  2015-01-05       Impact factor: 4.104

  5 in total

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