Literature DB >> 30304986

A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder.

Joanna Hellmuth1, Benedetta Milanini1, Eliezer Masliah2, Maria Carmela Tartaglia3, Miranda B Dunlop4, David J Moore5, Shireen Javandel1, Saskia DeVaughn1, Victor Valcour1.   

Abstract

We discuss the challenges associated with diagnosing neurodegenerative disorders in older adults living with HIV, illustrated through a case report where neurologic co-diagnosis of Alzheimer's disease (AD) and HIV-associated Neurocognitive Disorder (HAND) are considered. The patient was followed and evaluated for over 4 years and underwent post-mortem neuropathologic evaluation. Further work is needed to identify diagnostic tests that can adequately distinguish HAND from early stage neurodegenerative disorders among older adults living with HIV and cognitive changes.

Entities:  

Keywords:  Alzheimer’s disease; HIV-associated neurocognitive disorder; dementia; neuropathology; neuropsychological testing

Mesh：

Year:  2018        PMID： 30304986      PMCID： PMC6226354          DOI： 10.1080/13554794.2018.1530362

Source DB:  PubMed          Journal:  Neurocase        ISSN： 1355-4794            Impact factor:   0.881


  39 in total

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  6 in total

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