Literature DB >> 3030299

Tumor necrosis factor stimulates gelatinase and collagenase production by granulation tissue in culture.

H Nakagawa, H Kitagawa, Y Aikawa.   

Abstract

Tumor necrosis factor (TNF, 2.6 X 10(-11)-10(-9) M) caused an increase in the production of active gelatinase and latent collagenase by granulation tissue in culture. As determined by SDS-substrate polyacrylamide gel electrophoresis, granulation tissue produced mainly two species of gelatinase with molecular weights of 64 kDa and 57 kDa, and an additional 80-kDa gelatinase was produced by TNF treatment. The results suggest that TNF may play a role in a rapid collagen turnover in the carrageenin-induced granulation tissue in rats.

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Year:  1987        PMID： 3030299     DOI： 10.1016/0006-291x(87)91483-5

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

1.  Inflammation in neuroviral diseases.

Authors:  Pascale Giraudon; Arlette Bernard
Journal:  J Neural Transm (Vienna)       Date:  2010-08       Impact factor: 3.575

2.  Glomerular basement membrane-containing immune complexes stimulate tumor necrosis factor and interleukin-1 production by human monocytes.

Authors:  M C Vissers; J C Fantone; R Wiggins; S L Kunkel
Journal:  Am J Pathol       Date:  1989-01       Impact factor: 4.307

3.  Explorative study of interleukin levels in the human cornea.

Authors:  J Becker; S Salla; U Dohmen; C Redbrake; M Reim
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1995-12       Impact factor: 3.117

4.  Production of matrix metalloproteinases 2 and 3 (stromelysin) by stromal cells of giant cell tumor of bone.

Authors:  Y Sasaguri; S Komiya; K Sugama; K Suzuki; A Inoue; M Morimatsu; H Nagase
Journal:  Am J Pathol       Date:  1992-09       Impact factor: 4.307

Review 5.  Interstitial fibrosis and growth factors.

Authors:  J A Lasky; A R Brody
Journal:  Environ Health Perspect       Date:  2000-08       Impact factor: 9.031

6.  Basement membrane and repair of injury to peripheral nerve: defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1.

Authors:  M La Fleur; J L Underwood; D A Rappolee; Z Werb
Journal:  J Exp Med       Date:  1996-12-01       Impact factor: 14.307
  6 in total

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