| Literature DB >> 30302496 |
Abstract
Major progress has been made in the treatment of malignant melanoma during recent years. On the one hand, reliable evidence-based recommendations regarding surgical resection as well as lymph node management have been established on the basis of results from randomized multicenter studies. On the other hand, the advent of targeted therapies has led to spectacular improvements in the treatment of metastasized melanomas. Knowledge concerning treatment algorithms and updates thereof is also essential for maxillofacial surgeons. The German S3 guideline on diagnosis and treatment of melanoma was published in 2013 and revised in 2016 and 2018. This article informs readers about these developments and addresses the items relevant for treatment of head and neck melanomas in particular.Entities:
Keywords: Immunotherapy; Neck dissection; Resection margins; Sentinel lymph node biopsy; Skin neoplasms; Targeted therapy
Mesh:
Year: 2018 PMID: 30302496 DOI: 10.1007/s00106-018-0573-7
Source DB: PubMed Journal: HNO ISSN: 0017-6192 Impact factor: 1.284