| Literature DB >> 30302193 |
Zachary J Brown1, Bernd Heinrich1, Tim F Greten1.
Abstract
Hepatocellular carcinoma (HCC) is a major health problem worldwide with limited systemic therapies available. Immunotherapy is a fast-moving field that is quickly evolving as a treatment for HCC with three recent clinical trials published treating HCC with immune checkpoint inhibitors with promising results. Checkpoint inhibition may lead to a unique adverse event profile with the potential to cause immune-related adverse events by unbalancing the immune system. Here, we report a case of a 61-year-old male with advanced HCC who developed a shellfish allergy after completing three cycles of combination of tremelimumab and durvalumab therapy.Entities:
Keywords: allergy; checkpoint inhibitors; durvalumab; hepatocellular carcinoma; immunotherapy; tremelimumab
Year: 2018 PMID: 30302193 PMCID: PMC6168040 DOI: 10.2217/hep-2017-0021
Source DB: PubMed Journal: Hepat Oncol ISSN: 2045-0923