| Literature DB >> 30302052 |
Vikrant Sood1, Juhi Chawla2, Bikrant B Lal1, Rajeev Khanna1, Chhagan Bihari2, Seema Alam1.
Abstract
A 10-year-old female child, a known case of Beta-Thalassemia major with superimposed chronic Hepatitis C Viral (HCV) infection, underwent bone marrow transplantation and presented, 7 months later, with worsening hepatic functions and skin rash. Considering the wide variety of possible etiologies, she was evaluated and later confirmed as a case of hepatic dysfunction secondary to HCV related hepatic injury with concomitant chronic graft versus host disease (dermatological involvement only).Entities:
Keywords: ALT, Alanine Aminotransferase; AST, Aspartate Aminotransferase; BMT, Bone Marrow Transplantation; DAA, Direct-Acting Antiviral; DILI, Drug Induced Liver Injury; GVHD, Graft Versus Host Disease; HAI, Hepatic Activity Index; HCV, Hepatitis C Virus; MRI, Magnetic Resonance Imaging; RNA, Ribonucleic Acid; bone marrow transplantation; graft versus host disease; pediatric hepatitis C infection
Year: 2018 PMID： 30302052 PMCID： PMC6175742 DOI： 10.1016/j.jceh.2018.04.014
Source DB: PubMed Journal: J Clin Exp Hepatol ISSN： 0973-6883