Literature DB >> 30301404

Potassium channels in the sinoatrial node and their role in heart rate control.

Qadeer Aziz1, Yiwen Li1, Andrew Tinker1.   

Abstract

Potassium currents determine the resting membrane potential and govern repolarisation in cardiac myocytes. Here, we review the various currents in the sinoatrial node focussing on their molecular and cellular properties and their role in pacemaking and heart rate control. We also describe how our recent finding of a novel ATP-sensitive potassium channel population in these cells fits into this picture.

Entities:  

Keywords:  ATP-sensitive potassium channel; heart rate; pacemaking; potassium channel; sinoatrial node

Mesh：

Substances：

Year:  2018        PMID： 30301404      PMCID： PMC6207292          DOI： 10.1080/19336950.2018.1532255

Source DB:  PubMed          Journal:  Channels (Austin)        ISSN： 1933-6950            Impact factor:   2.581


  119 in total

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Journal:  Front Physiol       Date:  2022-06-22       Impact factor: 4.755

5.  Ion channel mRNA distribution and expression in the sinoatrial node and right atrium of dogs and monkeys.

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Journal:  J Toxicol Pathol       Date:  2021-04-18       Impact factor: 1.628

6.  Mechanical activities of self-beating cardiomyocyte aggregates under mechanical compression.

Authors:  Ken Nakano; Naoya Nanri; Yoshinari Tsukamoto; Mitsuru Akashi
Journal:  Sci Rep       Date:  2021-07-26       Impact factor: 4.379
  6 in total

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