Dezhi Zhang1,2, Wenzhao Liang3, Min Zhang4, Ping Liang5, Ying Gu6, Ming Kuang7,8, Feng Cao9, Xiaoling Yu10, Fengyong Liu11, Jie Yu12. 1. a Chinese PLA General Hospital, Interventional Ultrasound , Beijing , China. 2. b Department of Ultrasound , First Hospital of Jilin University , ChangChun , China. 3. c China-Japan Union Hospital of Jilin University , Changchun , China. 4. d General Hospital of Xinjiang Military Region, Ultrasound , Urumqi , China. 5. e Department of Ultrasound , Chinese PLA General Hospital , Beijing , China. 6. f Chinese PLA General Hospital, Laser Medicine , Beijing , China. 7. g Department of Liver Surgery , The First Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. 8. h Division of Interventional Ultrasound , The First Affiliated Hospital of Sun Yat-sen University , Guangzhou , China. 9. i Chinese PLA General hospital, Cardiology , Beijing , China. 10. j Department of Interventional Ultrasound , Chinese PLA General Hospital , Beijing , China. 11. k Chinese PLA General Hospital, Interventional Radiology , Beijing , China. 12. l Interventional Ultrasound Department , Chinese PLA General Hospital , Beijing , China.
Abstract
PURPOSE: This study was conducted to compare a three-dimensional (3D) fusion image navigation system (FINS) with ultrasound (US) for guiding percutaneous microwave ablation (PMWA) for treatment of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: This is a retrospective, non-randomized, comparative study. Our team developed a 3D FINS and used it to guide PMWAs for HCCs in 19 patients (3D group) and compared the results to those of 24 PMWAs guided by US (US group). The complete ablation rate of the first session, the local tumor progression (LTP), intrahepatic recurrence and disease-free survival were compared between the groups. RESULTS: The 3D FINS was successfully applied in all 19 patients. The mean size of HCCs was 4.14 cm ±0.95 in 3D the group and 4.07 cm ±0.91 in the US group. Major complications were identified at 5.3% in the 3D group and 4.2% in the US group (p = .865). Average time of image fusion was 404.53 ± 161.84 s. There were more antenna insertions in the 3D group (3.68 ± 1.57) than in the US group (2.71 ± 1.12) (p = .02). The complete ablation rate of the first session was higher in the 3D group (94.7%) than in the US group (62.5%) (p = .034). The mean follow-up period was 11.4 months ±4.9 in the 3D group and 9.8 months ±5.5 in the US group. There were no significant differences in technique efficacy rate and LTP rate between the two groups. CONCLUSIONS: The 3D FINS could be a safe, feasible and effective technique for guiding PMWA of HCC, which could help an operator improve the complete ablation rate of the first session.
PURPOSE: This study was conducted to compare a three-dimensional (3D) fusion image navigation system (FINS) with ultrasound (US) for guiding percutaneous microwave ablation (PMWA) for treatment of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: This is a retrospective, non-randomized, comparative study. Our team developed a 3D FINS and used it to guide PMWAs for HCCs in 19 patients (3D group) and compared the results to those of 24 PMWAs guided by US (US group). The complete ablation rate of the first session, the local tumor progression (LTP), intrahepatic recurrence and disease-free survival were compared between the groups. RESULTS: The 3D FINS was successfully applied in all 19 patients. The mean size of HCCs was 4.14 cm ±0.95 in 3D the group and 4.07 cm ±0.91 in the US group. Major complications were identified at 5.3% in the 3D group and 4.2% in the US group (p = .865). Average time of image fusion was 404.53 ± 161.84 s. There were more antenna insertions in the 3D group (3.68 ± 1.57) than in the US group (2.71 ± 1.12) (p = .02). The complete ablation rate of the first session was higher in the 3D group (94.7%) than in the US group (62.5%) (p = .034). The mean follow-up period was 11.4 months ±4.9 in the 3D group and 9.8 months ±5.5 in the US group. There were no significant differences in technique efficacy rate and LTP rate between the two groups. CONCLUSIONS: The 3D FINS could be a safe, feasible and effective technique for guiding PMWA of HCC, which could help an operator improve the complete ablation rate of the first session.
Authors: Pascale Tinguely; Iwan Paolucci; Simeon J S Ruiter; Stefan Weber; Koert P de Jong; Daniel Candinas; Jacob Freedman; Jennie Engstrand Journal: Front Oncol Date: 2021-09-23 Impact factor: 6.244