| Literature DB >> 30297978 |
Dacheng Wu1,2, Keyan Wu1,2, Qingtian Zhu2, Weiming Xiao1,2, Qing Shan2, Zhigang Yan1,2, Jian Wu1,2, Bin Deng1,2, Yan Xue1,2, Weijuan Gong1,2,3, Guotao Lu1,2, Yanbing Ding1,2.
Abstract
[This corrects the article DOI: 10.1155/2018/3048532.].Entities:
Year: 2018 PMID: 30297978 PMCID: PMC6146555 DOI: 10.1155/2018/9878120
Source DB: PubMed Journal: Mediators Inflamm ISSN: 0962-9351 Impact factor: 4.711
Figure 6NLRP3 inhibitor MCC950 eliminated the protective effect of H-For on acute colitis in mice. (a) The experimental protocol with For and MCC950 in an acute colitis model. (b) Body weights of mice and (c) disease activity index (DAI) during the disease process. (d) Morphological changes in the mouse colons, (e) variations of colon length of mice, (f) representative HE staining, and (g) histological scores of colonic tissue. (h) Protein levels of claudin-1, occludin, and ZO-1 and (i) NLRP3, ASC, and IL-1β were analyzed by western blotting. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001.