Literature DB >> 30297320

Central Obesity, Faster Maturation, and 'PCOS' in Girls.

Francis de Zegher1, Abel López-Bermejo2, Lourdes Ibáñez3.   

Abstract

Polycystic ovary syndrome (PCOS) development commonly starts with a mismatch between pre- and postnatal weight gain, leading to hepatovisceral fat excess. To escape from such central obesity, girls may accelerate their growth and/or maturation. This homeostatic mechanism is lost upon reaching adult height, and PCOS may ensue. Prevention and/or treatment of PCOS should aim at reducing central fat excess.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  fatty liver; hirsutism; maturation; ovulation; polycystic ovary syndrome; visceral fat

Mesh：

Year:  2018        PMID： 30297320     DOI： 10.1016/j.tem.2018.09.005

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  20 in total

1.  Associations of childhood adiposity with menstrual irregularity and polycystic ovary syndrome in adulthood: the Childhood Determinants of Adult Health Study and the Bogalusa Heart Study.

Authors:  Y He; J Tian; L Blizzard; W H Oddy; T Dwyer; L A Bazzano; M Hickey; E W Harville; A J Venn
Journal:  Hum Reprod       Date:  2020-05-01       Impact factor: 6.918

2.  Circulating GDF15 concentrations in girls with low birth weight: effects of prolonged metformin treatment.

Authors:  Marta Díaz; Gemma Carreras-Badosa; Joan Villarroya; Aleix Gavaldà-Navarro; Judit Bassols; Francis de Zegher; Abel López-Bermejo; Francesc Villarroya; Lourdes Ibáñez
Journal:  Pediatr Res       Date:  2022-07-11       Impact factor: 3.953

Review 3.  Follicular Fluid: A Powerful Tool for the Understanding and Diagnosis of Polycystic Ovary Syndrome.

Authors:  Ana Teresa Brinca; Ana Cristina Ramalhinho; Ângela Sousa; António Hélio Oliani; Luiza Breitenfeld; Luís A Passarinha; Eugenia Gallardo
Journal:  Biomedicines       Date:  2022-05-27

4.  Association Between Early Life Weight Gain and Abdominal Fat Partitioning at 4.5 Years is Sex, Ethnicity, and Age Dependent.

Authors:  Suresh Anand Sadananthan; Mya Thway Tint; Navin Michael; Izzuddin M Aris; See Ling Loy; Kuan Jin Lee; Lynette Pei-Chi Shek; Fabian Kok Peng Yap; Kok Hian Tan; Keith M Godfrey; Melvin Khee-Shing Leow; Yung Seng Lee; Michael S Kramer; Peter D Gluckman; Yap Seng Chong; Neerja Karnani; Christiani Jeyakumar Henry; Marielle Valerie Fortier; S Sendhil Velan
Journal:  Obesity (Silver Spring)       Date:  2019-02-01       Impact factor: 5.002

Review 5.  Update on adrenarche.

Authors:  Selma Feldman Witchel; Bianca Pinto; Anne Claire Burghard; Sharon E Oberfield
Journal:  Curr Opin Pediatr       Date:  2020-08       Impact factor: 2.856

Review 6.  Normal and Premature Adrenarche.

Authors:  Robert L Rosenfield
Journal:  Endocr Rev       Date:  2021-11-16       Impact factor: 19.871

Review 7.  Polycystic Ovary Syndrome: Ontogeny in Adolescence.

Authors:  Christine M Burt Solorzano; Christopher R McCartney
Journal:  Endocrinol Metab Clin North Am       Date:  2021-01-11       Impact factor: 4.741

8.  Inactivating NHLH2 variants cause idiopathic hypogonadotropic hypogonadism and obesity in humans.

Authors:  A Kemal Topaloglu; Enver Simsek; Matthew A Kocher; Jamala Mammadova; Ece Bober; Leman Damla Kotan; Ihsan Turan; Can Celiloglu; Fatih Gurbuz; Bilgin Yuksel; Deborah J Good
Journal:  Hum Genet       Date:  2022-01-23       Impact factor: 5.881

Review 9.  Curtailing PCOS.

Authors:  Selma Feldman Witchel; Helena J Teede; Alexia S Peña
Journal:  Pediatr Res       Date:  2019-10-18       Impact factor: 3.756

10.  Pathogenesis of Reproductive and Metabolic PCOS Traits in a Mouse Model.

Authors:  Valentina Rodriguez Paris; Melissa C Edwards; Ali Aflatounian; Michael J Bertoldo; William L Ledger; David J Handelsman; Robert B Gilchrist; Kirsty A Walters
Journal:  J Endocr Soc       Date:  2021-04-07
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