Literature DB >> 3029660

Foodborne Snow Mountain agent gastroenteritis in a school cafeteria.

C Guest, K C Spitalny, H P Madore, K Pray, R Dolin, J E Herrmann, N R Blacklow.   

Abstract

In 1984, an outbreak of gastroenteritis occurred at a school with 1,860 students in Brooklyn, NY. In a single-stage cluster sample of 375 students, 129 (34%) had illnesses that met our case definition of vomiting or diarrhea. The mean incubation period was 26 hours, and the mean illness duration was 24 hours. All case students had eaten in the cafeteria on at least one day between Nov 13 and 16, compared with 174/214 (81%) noncase students (P = 10(-8), Fisher exact test). Foods implicated were french fries (relative risk 1.7, 95% confidence limits 1.4, 2.0) and hamburgers (relative risk 1.6, 95%, confidence limits 1.2, 2.1). Two cafeteria employees had served those foods while affected by diarrhea. By a recently developed blocking enzyme-linked immunosorbent assay, six of 11 (55%) case students showed fourfold antibody increases between acute- and convalescent-phase serum samples for Snow Mountain agent, a Norwalk-like virus, compared with one of ten (10%) noncase students (P = .04, Fisher exact test). We strongly suspect, but cannot document conclusively, that the Snow Mountain agent was spread to students on a vector of hot foods contaminated by ill food handlers. Implicated foods conferred low relative risks and could only have accounted for 74% of cases of illness. The strong association between cafeteria exposure and illness, therefore, suggests that additional modes of spread occurred.

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Year:  1987        PMID: 3029660

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  8 in total

Review 1.  Contemporary issues: diseases with a food vector.

Authors:  D L Archer; F E Young
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Authors:  J P Brinker; N R Blacklow; X Jiang; M K Estes; C L Moe; J E Herrmann
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3.  Detection of Norwalk virus and other genogroup 1 human caliciviruses by a monoclonal antibody, recombinant-antigen-based immunoglobulin M capture enzyme immunoassay.

Authors:  J P Brinker; N R Blacklow; M K Estes; C L Moe; K J Schwab; J E Herrmann
Journal:  J Clin Microbiol       Date:  1998-04       Impact factor: 5.948

4.  Subclass-specific serum antibody responses to recombinant Norwalk virus capsid antigen (rNV) in adults infected with Norwalk, Snow Mountain, or Hawaii virus.

Authors:  J J Treanor; X Jiang; H P Madore; M K Estes
Journal:  J Clin Microbiol       Date:  1993-06       Impact factor: 5.948

Review 5.  Outbreaks of food-borne and waterborne viral gastroenteritis.

Authors:  C W Hedberg; M T Osterholm
Journal:  Clin Microbiol Rev       Date:  1993-07       Impact factor: 26.132

6.  Characterization and seroepidemiology of a type 5 astrovirus associated with an outbreak of gastroenteritis in Marin County, California.

Authors:  K Midthun; H B Greenberg; J B Kurtz; G W Gary; F Y Lin; A Z Kapikian
Journal:  J Clin Microbiol       Date:  1993-04       Impact factor: 5.948

7.  Production of a monoclonal antibody against the Snow Mountain agent of gastroenteritis by in vitro immunization of murine spleen cells.

Authors:  J Treanor; R Dolin; H P Madore
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

Review 8.  Norovirus disease: changing epidemiology and host susceptibility factors.

Authors:  Anne M Hutson; Robert L Atmar; Mary K Estes
Journal:  Trends Microbiol       Date:  2004-06       Impact factor: 17.079

  8 in total

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