Literature DB >> 30295724

Extracting chemical-protein relations using attention-based neural networks.

Sijia Liu1,2, Feichen Shen1, Ravikumar Komandur Elayavilli1, Yanshan Wang1, Majid Rastegar-Mojarad1,3, Vipin Chaudhary2, Hongfang Liu1.   

Abstract

Relation extraction is an important task in the field of natural language processing. In this paper, we describe our approach for the BioCreative VI Task 5: text mining chemical-protein interactions. We investigate multiple deep neural network (DNN) models, including convolutional neural networks, recurrent neural networks (RNNs) and attention-based (ATT-) RNNs (ATT-RNNs) to extract chemical-protein relations. Our experimental results indicate that ATT-RNN models outperform the same models without using attention and the ATT-gated recurrent unit (ATT-GRU) achieves the best performing micro average F1 score of 0.527 on the test set among the tested DNNs. In addition, the result of word-level attention weights also shows that attention mechanism is effective on selecting the most important trigger words when trained with semantic relation labels without the need of semantic parsing and feature engineering. The source code of this work is available at https://github.com/ohnlp/att-chemprot.

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Year:  2018        PMID: 30295724      PMCID: PMC6174551          DOI: 10.1093/database/bay102

Source DB:  PubMed          Journal:  Database (Oxford)        ISSN: 1758-0463            Impact factor:   3.451


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