Literature DB >> 30295656

Application of Design Aspects in Uniaxial Loading Machine Development.

Robert P Thoerner1, Jonathan D King1, Marnie M Saunders2.   

Abstract

In terms of accurate and precise mechanical testing, machines run the continuum. Whereas commercial platforms offer excellent accuracy, they can be cost-prohibitive, often priced in the $100,000 - $200,000 price range. At the other extreme are stand-alone manual devices that often lack repeatability and accuracy (e.g., a manual crank device). However, if a single use is indicated, it is over-engineering to design and machine something overly elaborate. Nonetheless, there are occasions where machines are designed and built in-house to accomplish a motion not attainable with the existing machines in the laboratory. Described in detail here is one such device. It is a loading platform that enables pure uniaxial loading. Standard loading machines typically are biaxial in that linear loading occurs along the axis and rotary loading occurs about the axis. During testing with these machines, a load is applied to one end of the specimen while the other end remains fixed. These systems are not capable of conducting pure axial testing in which tension/compression is applied equally to the specimen ends. The platform developed in this paper enables the equal and opposite loading of specimens. While it can be used for compression, here the focus is on its use in pure tensile loading. The device incorporates commercial load cells and actuators (movers) and, as is the case with machines built in-house, a frame is machined to hold the commercial parts and fixtures for testing.

Mesh:

Year:  2018        PMID: 30295656      PMCID: PMC6235243          DOI: 10.3791/58168

Source DB:  PubMed          Journal:  J Vis Exp        ISSN: 1940-087X            Impact factor:   1.355


  8 in total

Review 1.  Techniques for mechanical stimulation of cells in vitro: a review.

Authors:  T D Brown
Journal:  J Biomech       Date:  2000-01       Impact factor: 2.712

2.  Development of a cost-effective loading machine for biomechanical evaluation of mouse transgenic models.

Authors:  M M Saunders; H J Donahue
Journal:  Med Eng Phys       Date:  2004-09       Impact factor: 2.242

3.  The biomechanics of human femurs in axial and torsional loading: comparison of finite element analysis, human cadaveric femurs, and synthetic femurs.

Authors:  M Papini; R Zdero; E H Schemitsch; P Zalzal
Journal:  J Biomech Eng       Date:  2007-02       Impact factor: 2.097

4.  Design, fabrication and characterization of a pure uniaxial microloading system for biologic testing.

Authors:  Jonathan D King; Spencer L York; Marnie M Saunders
Journal:  Med Eng Phys       Date:  2016-02-18       Impact factor: 2.242

5.  Design and Use of a Novel Bioreactor for Regeneration of Biaxially Stretched Tissue-Engineered Vessels.

Authors:  Angela Hai Huang; Yong-Ung Lee; Elizabeth A Calle; Michael Boyle; Barry C Starcher; Jay D Humphrey; Laura E Niklason
Journal:  Tissue Eng Part C Methods       Date:  2015-03-20       Impact factor: 3.056

6.  Adaptation of a planar microbiaxial optomechanical device for the tubular biaxial microstructural and macroscopic characterization of small vascular tissues.

Authors:  Joseph T Keyes; Darren G Haskett; Urs Utzinger; Mohamad Azhar; Jonathan P Vande Geest
Journal:  J Biomech Eng       Date:  2011-07       Impact factor: 2.097

7.  Osteoblasts subjected to mechanical strain inhibit osteoclastic differentiation and bone resorption in a co-culture system.

Authors:  Jianyu Li; Zongming Wan; Hui Liu; Hao Li; Lu Liu; Ruixin Li; Yong Guo; Wei Chen; Xinchang Zhang; Xizheng Zhang
Journal:  Ann Biomed Eng       Date:  2013-04-23       Impact factor: 3.934

8.  Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions.

Authors:  B Poulet; R de Souza; A V Kent; L Saxon; O Barker; A Wilson; Y-M Chang; M Cake; A A Pitsillides
Journal:  Osteoarthritis Cartilage       Date:  2015-02-02       Impact factor: 6.576

  8 in total

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