Literature DB >> 30295651

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse (POP) Quantification System.

María Luisa Sánchez-Ferrer1, María Teresa Prieto-Sánchez2, Carlos Moya-Jiménez3, Jaime Mendiola4, Carmen María García-Hernández3, Ana Carmona-Barnosi3, Anibal Nieto1, Alberto M Torres-Cantero5.   

Abstract

Anogenital distance (AGD) is a sexually dimorphic attribute, twice longer in males than in females, and a marker of intrauterine hormonal environment. Interest in AGD measurements is increasing due to mounting evidence on their potential clinical implications. A parallel set of perineal measurements, the Pelvic Organ Prolapse Quantification System (POP-Q), include similar, but not exactly the same, landmarks: the perineal body (PB) and the genital hiatus (GH) lengths. However, clinical reproducibility of both perineal measurements and their usefulness to describe perineal anthropometry needs to be elucidated. To our knowledge, there is no publication in video format showing the methodology of these measurements. The main objective of this work is to show how to properly perform perineal anthropometry, including measurements of the AGD in its two variants [anoclitoral (AGDAC) and anofourchette (AGDAF)], genital hiatus (GH) and perineal body (PB). Moreover, we explored if there were differences in these measurements in women with and without Pelvic Organ Prolapse (POP). We research whether the anthropometric characteristics of the perineum, such as AGD (which is determined prenatally), may be altered in these women and be an independent etiological factor for pelvic floor dysfunction. We show two different ways of measuring perineal lengths, as they might be quite comparable. Our suggestion is that unifying perineal measurements could be useful for clinical and biomedical investigation. More studies are needed in order to compare GH and PB measurements and its AGD counterparts to analyze which procedures are more reproducible with less intra and interobserver variability.

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Year:  2018        PMID: 30295651      PMCID: PMC6235246          DOI: 10.3791/57912

Source DB:  PubMed          Journal:  J Vis Exp        ISSN: 1940-087X            Impact factor:   1.355


  32 in total

1.  Urethral development in the fetal rabbit and induction of hypospadias: a model for human development.

Authors:  E A Kurzrock; P Jegatheesan; G R Cunha; L S Baskin
Journal:  J Urol       Date:  2000-11       Impact factor: 7.450

2.  The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction.

Authors:  R C Bump; A Mattiasson; K Bø; L P Brubaker; J O DeLancey; P Klarskov; B L Shull; A R Smith
Journal:  Am J Obstet Gynecol       Date:  1996-07       Impact factor: 8.661

3.  Sexing mouse pups.

Authors:  L W Greenham; V Greenham
Journal:  Lab Anim       Date:  1977-07       Impact factor: 2.471

4.  First-trimester determination of fetal gender by ultrasound: measurement of the ano-genital distance.

Authors:  A Arfi; J Cohen; G Canlorbe; S Bendifallah; I Thomassin-Naggara; E Darai; A Benachi; J S Arfi
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2016-06-09       Impact factor: 2.435

5.  Polycystic ovary syndrome is associated with anogenital distance, a marker of prenatal androgen exposure.

Authors:  Yingchen Wu; Guangzheng Zhong; Shengfu Chen; Chengyu Zheng; Dehua Liao; Meiqing Xie
Journal:  Hum Reprod       Date:  2017-04-01       Impact factor: 6.918

6.  Shorter anogenital distance correlates with undescended testis: a detailed genital anthropometric analysis in human newborns.

Authors:  Viral G Jain; Arbinder Kumar Singal
Journal:  Hum Reprod       Date:  2013-07-09       Impact factor: 6.918

7.  Presence of polycystic ovary syndrome is associated with longer anogenital distance in adult Mediterranean women.

Authors:  María L Sánchez-Ferrer; Jaime Mendiola; Ana I Hernández-Peñalver; Shiana Corbalán-Biyang; Ana Carmona-Barnosi; María T Prieto-Sánchez; Aníbal Nieto; Alberto M Torres-Cantero
Journal:  Hum Reprod       Date:  2017-11-01       Impact factor: 6.918

Review 8.  A systematic review of clinical studies on hereditary factors in pelvic organ prolapse.

Authors:  Sabrina L Lince; Leon C van Kempen; Mark E Vierhout; Kirsten B Kluivers
Journal:  Int Urogynecol J       Date:  2012-03-16       Impact factor: 2.894

9.  Anogenital distance is related to ovarian follicular number in young Spanish women: a cross-sectional study.

Authors:  Jaime Mendiola; Manuela Roca; Lidia Mínguez-Alarcón; Maria-Pilar Mira-Escolano; José J López-Espín; Emily S Barrett; Shanna H Swan; Alberto M Torres-Cantero
Journal:  Environ Health       Date:  2012-12-08       Impact factor: 5.984

10.  Decrease in anogenital distance among male infants with prenatal phthalate exposure.

Authors:  Shanna H Swan; Katharina M Main; Fan Liu; Sara L Stewart; Robin L Kruse; Antonia M Calafat; Catherine S Mao; J Bruce Redmon; Christine L Ternand; Shannon Sullivan; J Lynn Teague
Journal:  Environ Health Perspect       Date:  2005-08       Impact factor: 9.031

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  1 in total

1.  A Systematic Review of Anogenital Distance and Gynecological Disorders: Endometriosis and Polycystic Ovary Syndrome.

Authors:  Zhenyan Pan; Fangfang Zhu; Kai Zhou
Journal:  Front Endocrinol (Lausanne)       Date:  2021-07-22       Impact factor: 5.555

  1 in total

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