| Literature DB >> 30295064 |
Phu H Dang1, Linh T T Nguyen1, Hue T T Nguyen1, Tho H Le1, Truong N V Do1, Hai X Nguyen1, Nghia D Le1, Mai T T Nguyen1,2, Nhan T Nguyen1,2.
Abstract
From an EtOAc-soluble fraction of the stem barks of Swintonia floribunda (Anacardiaceae), one new dimeric alkylresorcinol named integracin E (1), together with 4 known compounds (2-5) were isolated. Their chemical structures were elucidated based on the spectroscopic data interpretation. The absolute configuration of 1 was determined by the specific rotation analysis of its acid-catalyzed hydrolysis product. Compound 1 showed potent tyrosinase inhibitory activity with an IC50 value of 48.2 μM.Entities:
Keywords: Anacardiaceae; alkylresorcinol; tyrosinase inhibitory
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Year: 2018 PMID： 30295064 DOI： 10.1080/14786419.2018.1509329
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861