Literature DB >> 3029498

The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3.

R Kumar.   

Abstract

Much has been learned about the formation of the active metabolite of vitamin D3, 1,25-dihydroxyvitamin D3. Information concerning its formation and catabolism has allowed a clear understanding of factors involved in the maintenance of plasma concentrations of the hormone. The effects of 1,25-dihydroxyvitamin D3 on calcium transporting cells in the intestine are marked and well defined. The tissue (intestinal tissue) is easily isolated and manipulated and hence, this is an ideal tissue in which to examine the mechanism of divalent cation transport. The mechanism by which 1,25-dihydroxyvitamin D3 brings about this effect should help in understanding sterol hormone action.

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Year:  1986        PMID： 3029498     DOI： 10.1038/ki.1986.258

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  10 in total

Review 1.  Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment.

Authors:  Peter J Tebben; Ravinder J Singh; Rajiv Kumar
Journal:  Endocr Rev       Date:  2016-09-02       Impact factor: 19.871

2.  Bone mineralization and calciotropic hormones in children with hyperthyroidism. Effects of methimazole therapy.

Authors:  G Saggese; S Bertelloni; G I Baroncelli
Journal:  J Endocrinol Invest       Date:  1990 Jul-Aug       Impact factor: 4.256

3.  The cause of maintained hypercalciuria after the surgical cure of primary hyperparathyroidism is a defect in renal calcium reabsorption.

Authors:  M L Farias; A G Delgado; D Rosenthal; J G Vieira; T Kasamatsu; M J Lazarevitch; M F Pereira; M B Lima
Journal:  J Endocrinol Invest       Date:  1996-01       Impact factor: 4.256

4.  Local action of phosphate depletion and insulin-like growth factor 1 on in vitro production of 1,25-dihydroxyvitamin D by cultured mammalian kidney cells.

Authors:  L Condamine; C Menaa; F Vrtovsnik; F Vztovsnik; G Friedlander; M Garabédian
Journal:  J Clin Invest       Date:  1994-10       Impact factor: 14.808

5.  Comparison of the effect of daily versus bolus dose maternal vitamin D3 supplementation on the 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 ratio.

Authors:  Hemamalini Ketha; Tom D Thacher; Sara S Oberhelman; Philip R Fischer; Ravinder J Singh; Rajiv Kumar
Journal:  Bone       Date:  2018-02-24       Impact factor: 4.398

Review 6.  The serum vitamin D metabolome: What we know and what is still to discover.

Authors:  Robert C Tuckey; Chloe Y S Cheng; Andrzej T Slominski
Journal:  J Steroid Biochem Mol Biol       Date:  2018-09-08       Impact factor: 4.292

7.  Vitamin D status and CYP27B1-1260 promoter polymorphism in Tunisian patients with systemic lupus erythematosus.

Authors:  Raouia Fakhfakh; Sawsan Feki; Aida Elleuch; Manel Neifar; Sameh Marzouk; Nesrine Elloumi; Hend Hachicha; Olfa Abida; Zouhir Bahloul; Fatma Ayadi; Hatem Masmoudi
Journal:  Mol Genet Genomic Med       Date:  2021-02-17       Impact factor: 2.183

8.  The Pathophysiology of Secondary Hyperparathyroidism and the Consequences of Uncontrolled Mineral Metabolism in Chronic Kidney Disease: The Role of COSMOS.

Authors:  Jorge B Cannata-Andía; Fernando Carrera
Journal:  NDT Plus       Date:  2008-01

9.  Validation and Determination of 25(OH) Vitamin D and 3-Epi25(OH)D3 in Breastmilk and Maternal- and Infant Plasma during Breastfeeding.

Authors:  Jennifer Gjerde; Marian Kjellevold; Lisbeth Dahl; Torill Berg; Annbjørg Bøkevoll; Maria Wik Markhus
Journal:  Nutrients       Date:  2020-07-29       Impact factor: 5.717

10.  CYP27B1 Gene Polymorphism rs10877012 in Patients Diagnosed with Colorectal Cancer.

Authors:  Maria Latacz; Jadwiga Snarska; Elżbieta Kostyra; Konrad Wroński; Ewa Fiedorowicz; Huub Savelkoul; Beata Jarmołowska; Janusz Płomiński; Roman Grzybowski; Anna Cieślińska
Journal:  Nutrients       Date:  2020-04-03       Impact factor: 5.717
  10 in total

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