Literature DB >> 30292916

Design strategies for chemical-stimuli-responsive programmable nanotherapeutics.

Muhammad Gulfam1, Fitsum Feleke Sahle1, Tao L Lowe2.   

Abstract

Chemical-stimuli-responsive nanotherapeutics have gained great interest in drug delivery and diagnosis applications. These nanotherapeutics are designed to respond to specific internal stimuli including pH, ionic strength, redox, reactive oxygen species, glucose, enzymes, ATP and hypoxia for site-specific and responsive or triggered release of payloads and/or biomarker detections. This review systematically and comprehensively addresses up-to-date technological and design strategies, and challenges nanomaterials to be used for triggered release and sensing in response to chemical stimuli.
Copyright © 2018 Elsevier Ltd. All rights reserved.

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Year:  2018        PMID： 30292916      PMCID： PMC6372326          DOI： 10.1016/j.drudis.2018.09.019

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  122 in total

Review 1.  Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple.

Authors:  F Q Schafer; G R Buettner
Journal:  Free Radic Biol Med       Date:  2001-06-01       Impact factor: 7.376

Review 2.  Nasal drug delivery - recent developments and future prospects.

Authors:  Lisbeth Illum
Journal:  J Control Release       Date:  2012-01-24       Impact factor: 9.776

Review 3.  Dysregulated pH: a perfect storm for cancer progression.

Authors:  Bradley A Webb; Michael Chimenti; Matthew P Jacobson; Diane L Barber
Journal:  Nat Rev Cancer       Date:  2011-08-11       Impact factor: 60.716

4.  Real-Time Monitoring of ATP-Responsive Drug Release Using Mesoporous-Silica-Coated Multicolor Upconversion Nanoparticles.

Authors:  Jinping Lai; Birju P Shah; Yixiao Zhang; Letao Yang; Ki-Bum Lee
Journal:  ACS Nano       Date:  2015-04-15       Impact factor: 15.881

Review 5.  Stimuli-sensitive nanopreparations for combination cancer therapy.

Authors:  Aditi Jhaveri; Pranali Deshpande; Vladimir Torchilin
Journal:  J Control Release       Date:  2014-05-10       Impact factor: 9.776

6.  Targeting tumor hypoxia with stimulus-responsive nanocarriers in overcoming drug resistance and monitoring anticancer efficacy.

Authors:  Zhiqi Xie; Wangwei Guo; Ningning Guo; Mingyi Huangfu; Huina Liu; Mengting Lin; WenHong Xu; Jiejian Chen; TianTian Wang; Qichun Wei; Min Han; Jianqing Gao
Journal:  Acta Biomater       Date:  2018-03-13       Impact factor: 8.947

Review 7.  Recent advances in polymeric micelles for anti-cancer drug delivery.

Authors:  Swati Biswas; Preeti Kumari; Prit Manish Lakhani; Balaram Ghosh
Journal:  Eur J Pharm Sci       Date:  2015-12-31       Impact factor: 4.384

8.  Hydrogen Peroxide-Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury.

Authors:  Soochan Bae; Minhyung Park; Changsun Kang; Serkan Dilmen; Tae Hi Kang; Dong Goo Kang; Qingen Ke; Seung Uk Lee; Dongwon Lee; Peter M Kang
Journal:  J Am Heart Assoc       Date:  2016-11-14       Impact factor: 5.501

9.  Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy.

Authors:  Hong-Mei Liu; Ya-Fei Zhang; Yan-Dong Xie; Yi-Fan Cai; Bai-Yang Li; Wen Li; Ling-Yu Zeng; Yu-Ling Li; Ru-Tong Yu
Journal:  Int J Nanomedicine       Date:  2017-02-08

10.  Enzyme-responsive polyion complex (PIC) nanoparticles for the targeted delivery of antimicrobial polymers.

Authors:  Ignacio Insua; Evangelos Liamas; Zhenyu Zhang; Anna F A Peacock; Anne Marie Krachler; Francisco Fernandez-Trillo
Journal:  Polym Chem       Date:  2016-03-24       Impact factor: 5.582
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  7 in total

1.  Delivery of an ectonucleotidase inhibitor with ROS-responsive nanoparticles overcomes adenosine-mediated cancer immunosuppression.

Authors:  Chengqiong Mao; Stacy Yeh; Juan Fu; Mercedes Porosnicu; Alexandra Thomas; Gregory L Kucera; Konstantinos I Votanopoulos; Shaomin Tian; Xin Ming
Journal:  Sci Transl Med       Date:  2022-06-08       Impact factor: 19.319

2.  Specific bFGF targeting of KIM-1 in ischemic kidneys protects against renal ischemia-reperfusion injury in rats.

Authors:  Siqi Song; Xianglin Hou; Weiwei Zhang; Xinyu Liu; Wei Wang; Xiaoya Wang; Wenxuan Cao; Yujun Xia; Wei Chen; Chunying Shi
Journal:  Regen Biomater       Date:  2022-05-12

3.  Design strategies for programmable oligonucleotide nanotherapeutics.

Authors:  Fitsum Feleke Sahle; Tao L Lowe
Journal:  Drug Discov Today       Date:  2019-09-13       Impact factor: 7.851

4.  Fabrication of Polymer Micelles with Zwitterionic Shell and Biodegradable Core for Reductively Responsive Release of Doxorubicin.

Authors:  Junting Jiang; Junbo Li; Biyu Zhou; Chaohuang Niu; Wendi Wang; Wenlan Wu; Ju Liang
Journal:  Polymers (Basel)       Date:  2019-06-09       Impact factor: 4.329

Review 5.  Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections.

Authors:  Arturo Sánchez; Susana P Mejía; Jahir Orozco
Journal:  Molecules       Date:  2020-08-18       Impact factor: 4.411

Review 6.  Nanoparticle-based delivery systems modulate the tumor microenvironment in pancreatic cancer for enhanced therapy.

Authors:  Ming Jia; Dan Zhang; Chunxiang Zhang; Chunhong Li
Journal:  J Nanobiotechnology       Date:  2021-11-22       Impact factor: 10.435

7.  A Unique Core-Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects.

Authors:  Bei Cheng; Hye-Hyun Ahn; Hwanhee Nam; Zirui Jiang; Feng J Gao; Il Minn; Martin G Pomper
Journal:  Pharmaceutics       Date:  2022-02-07       Impact factor: 6.525
  7 in total

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