Literature DB >> 3029268

Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes.

F Gotch, A McMichael, G Smith, B Moss.   

Abstract

Human cytotoxic T cells specific for influenza A virus were tested for recognition of each of the ten influenza A virus proteins expressed in target cells using recombinant vaccinia viruses. They recognized the matrix M1, polymerase PB2, and nucleoproteins of influenza virus in association with MHC class I antigens. These internal viral proteins were seen by CTL in conjunction with one or more of the available dependent HLA gene products. There was no detectable recognition of influenza virus surface glycoproteins in target cells.

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Year:  1987        PMID: 3029268      PMCID: PMC2188513          DOI: 10.1084/jem.165.2.408

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  19 in total

Review 1.  MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness.

Authors:  R M Zinkernagel; P C Doherty
Journal:  Adv Immunol       Date:  1979       Impact factor: 3.543

2.  Cytotoxic T cells to type A influenza virus; viral hemagglutinin induces A-strain specificity while infected cells confer cross-reactive cytotoxicity.

Authors:  H J Zweerink; B A Askonas; D Millican; S A Courtneidge; J J Skehel
Journal:  Eur J Immunol       Date:  1977-09       Impact factor: 5.532

Review 3.  Inhibition of human T lymphocyte function with monoclonal antibodies.

Authors:  D W Dongworth; A J McMichael
Journal:  Br Med Bull       Date:  1984-07       Impact factor: 4.291

4.  General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes.

Authors:  M Mackett; G L Smith; B Moss
Journal:  J Virol       Date:  1984-03       Impact factor: 5.103

5.  Construction and characterization of an infectious vaccinia virus recombinant that expresses the influenza hemagglutinin gene and induces resistance to influenza virus infection in hamsters.

Authors:  G L Smith; B R Murphy; B Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1983-12       Impact factor: 11.205

6.  Cytotoxic T-cell immunity to influenza.

Authors:  A J McMichael; F M Gotch; G R Noble; P A Beare
Journal:  N Engl J Med       Date:  1983-07-07       Impact factor: 91.245

7.  Declining T-cell immunity to influenza, 1977-82.

Authors:  A J McMichael; F M Gotch; D W Dongworth; A Clark; C W Potter
Journal:  Lancet       Date:  1983-10-01       Impact factor: 79.321

8.  Virus specificity of human influenza virus-immune cytotoxic T cells.

Authors:  W E Biddison; S Shaw; D L Nelson
Journal:  J Immunol       Date:  1979-02       Impact factor: 5.422

9.  Cytotoxic T lymphocyte recognition of the influenza hemagglutinin gene product expressed by DNA-mediated gene transfer.

Authors:  T J Braciale; V L Braciale; T J Henkel; J Sambrook; M J Gething
Journal:  J Exp Med       Date:  1984-02-01       Impact factor: 14.307

10.  HLA B37 determines an influenza A virus nucleoprotein epitope recognized by cytotoxic T lymphocytes.

Authors:  A J McMichael; F M Gotch; J Rothbard
Journal:  J Exp Med       Date:  1986-11-01       Impact factor: 14.307

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  91 in total

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Authors:  J T Voeten; T M Bestebroer; N J Nieuwkoop; R A Fouchier; A D Osterhaus; G F Rimmelzwaan
Journal:  J Virol       Date:  2000-08       Impact factor: 5.103

2.  Contribution of T-cell receptor repertoire breadth to the dominance of epitope-specific CD8+ T-lymphocyte responses.

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3.  The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype.

Authors:  A C M Boon; G de Mutsert; Y M F Graus; R A M Fouchier; K Sintnicolaas; A D M E Osterhaus; G F Rimmelzwaan
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4.  Toward a broadly protective influenza vaccine.

Authors:  Peter C Doherty; Anne Kelso
Journal:  J Clin Invest       Date:  2008-10       Impact factor: 14.808

5.  Expression of Epstein-Barr virus nuclear antigens in anti-IgM-stimulated B cells following recombinant vaccinia infection and their recognition by human cytotoxic T cells.

Authors:  R Khanna; C A Jacob; S R Burrows; M G Kurilla; E Kieff; I S Misko; T B Sculley; D J Moss
Journal:  Immunology       Date:  1991-11       Impact factor: 7.397

6.  Engineered influenza virions reveal the contributions of non-hemagglutinin structural proteins to vaccine mediated protection.

Authors:  Zhaochen Luo; Alanson W Girton; Brook E Heaton; Nicholas S Heaton
Journal:  J Virol       Date:  2021-03-03       Impact factor: 5.103

7.  HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.

Authors:  M J Koziel; D Dudley; N Afdhal; A Grakoui; C M Rice; Q L Choo; M Houghton; B D Walker
Journal:  J Clin Invest       Date:  1995-11       Impact factor: 14.808

8.  Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses.

Authors:  Yeping Sun; Jun Liu; Meng Yang; Feng Gao; Jianfang Zhou; Yoshihiro Kitamura; Bin Gao; Po Tien; Yuelong Shu; Aikichi Iwamoto; Zhu Chen; George F Gao
Journal:  J Gen Virol       Date:  2009-12-02       Impact factor: 3.891

9.  Human cytotoxic T cells stimulated by antigen on dendritic cells recognize the N, SH, F, M, 22K, and 1b proteins of respiratory syncytial virus.

Authors:  A H Cherrie; K Anderson; G W Wertz; P J Openshaw
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

10.  The inhibitor of cyclin-dependent kinases, olomoucine II, exhibits potent antiviral properties.

Authors:  Jitka Holcakova; Peter Tomasec; Joachim J Bugert; Eddie Cy Wang; Gavin Wg Wilkinson; Roman Hrstka; Vladimir Krystof; Miroslav Strnad; Borivoj Vojtesek
Journal:  Antivir Chem Chemother       Date:  2010-01-05
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