Literature DB >> 30292582

Prevalence of hepatic steatosis and its relation to liver function tests and lipid profile in patients at medical check-up.

P Briseño-Bass1, R Chávez-Pérez2, M López-Zendejas3.   

Abstract

INTRODUCTION AND AIMS: Nonalcoholic fatty liver disease has now become a worldwide health problem, and its dramatic increase is due to the prevalence of diseases such as obesity, type 2 diabetes mellitus, and metabolic syndrome. The aim of our study was to publish the current prevalence of hepatic steatosis in a Mexican population undergoing routine medical check-up, as well as to analyze its relation to BMI, liver function tests, and lipid profile.
MATERIALS AND METHODS: An observational, retrospective, cross-sectional study was conducted on patients that underwent medical check-up within the time frame of January 2011 and December 2015 at the Hospital San Javier. Patients included in the study were those with somatometry measurements (BMI), lipid profile, liver function tests, and abdominal ultrasound with a multi-frequency convex transducer.
RESULTS: We found that 65% of the patients presented with overweight or obesity and there was a 49.19% prevalence of hepatic steatosis in the study population. That prevalence was more frequent in men and hepatic steatosis was strongly linked to an increase in triglycerides, AST, and GGT and a decrease in HDL.
CONCLUSIONS: Establishing the technical aspects of the study was an important aid to having better correlation with and standardization of the accepted definitions, given that ultrasound is an adequate screening technique for an open population. Our results clearly showed a direct relation between hepatic steatosis and alterations in BMI, triglycerides, HDL, ALT, and GGT.
Copyright © 2018. Publicado por Masson Doyma México S.A.

Entities:  

Keywords:  Dislipidemia; Dyslipidemia; Fatty liver; Hígado graso; Liver function tests; Pruebas de función hepática; Ultrasonido; Ultrasound

Mesh:

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Year:  2018        PMID: 30292582     DOI: 10.1016/j.rgmx.2018.05.007

Source DB:  PubMed          Journal:  Rev Gastroenterol Mex (Engl Ed)        ISSN: 2255-534X


  1 in total

Review 1.  De vuelta a la clínica. Métodos I. Diseños de investigación. Mayor calidad de información, mayor certeza a la respuesta.

Authors:  Juan O Talavera; Ivonne Roy-García; Lino Palacios-Cruz; Rodolfo Rivas-Ruiz; Irma Hoyo; Marcela Pérez-Rodríguez
Journal:  Gac Med Mex       Date:  2019       Impact factor: 0.302

  1 in total

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