Literature DB >> 30291124

CAR T-cell Therapy for Solid Tumors?

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Abstract

Scientists have identified a wide variety of challenges preventing the development of effective CAR T-cell therapies for solid tumors, but they are investigating just as many potential solutions. Progress has been slow, but many researchers remain optimistic that successful CAR T-cell therapies, either alone or in combination with other treatments, will eventually be developed. ©2018 American Association for Cancer Research.

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Year:  2018        PMID: 30291124     DOI: 10.1158/2159-8290.CD-ND2018-008

Source DB:  PubMed          Journal:  Cancer Discov        ISSN: 2159-8274            Impact factor:   39.397


  2 in total

Review 1.  The making and function of CAR cells.

Authors:  Maja Zabel; Peter A Tauber; Winfried F Pickl
Journal:  Immunol Lett       Date:  2019-06-07       Impact factor: 3.685

2.  Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma.

Authors:  Giulia Agliardi; Anna Rita Liuzzi; Alastair Hotblack; Donatella De Feo; Nicolás Núñez; Cassandra L Stowe; Ekaterina Friebel; Francesco Nannini; Lukas Rindlisbacher; Thomas A Roberts; Rajiv Ramasawmy; Iwan P Williams; Bernard M Siow; Mark F Lythgoe; Tammy L Kalber; Sergio A Quezada; Martin A Pule; Sonia Tugues; Karin Straathof; Burkhard Becher
Journal:  Nat Commun       Date:  2021-01-19       Impact factor: 14.919

  2 in total

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