| Literature DB >> 30291113 |
Catharina Schuetz1, Manfred Hoenig1, Despina Moshous2,3, Christof Weinstock4, Martin Castelle2, Matthieu Bendavid2, Kristin Shimano5, Vanessa Tolbert5, Ansgar S Schulz1, Christopher C Dvorak5.
Abstract
New-onset autoimmune hemolytic anemia (AIHA) occurs in 2% to 6% of pediatric patients post-hematopoietic stem cell transplantation (HSCT) and is a significant complication. Incomplete immune recovery following HSCT may predispose to immune dysregulation including autoimmune cytopenias. We describe an innovative therapy for AIHA refractory to proteasome inhibition. In potentially life-threatening AIHA in the context of HSCT, daratumumab may be an effective rescue therapy.Entities:
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Year: 2018 PMID: 30291113 PMCID: PMC6177653 DOI: 10.1182/bloodadvances.2018020883
Source DB: PubMed Journal: Blood Adv ISSN: 2473-9529